CILAPEN 250MG INJECTION

CILAPEN 250MG INJECTION is a combination medication containing Imipenem & Cilastatin. It is classified as a carbapenem antibiotic and is primarily used to treat severe bacterial infections. Imipenem is the active antibiotic component, while cilastatin acts to inhibit the renal enzyme dehydropeptidase I, thereby preventing the inactivation of imipenem in the kidneys, prolonging its antibacterial activity.

Ingredients:

• Imipenem: Imipenem is a broad-spectrum antibiotic belonging to the carbapenem class. It works by inhibiting bacterial cell wall synthesis, leading to the death of susceptible bacteria. Imipenem is effective against a wide range of Gram-positive and Gram-negative bacteria.
• Cilastatin: Cilastatin is a renal dehydropeptidase inhibitor that prevents the degradation of imipenem in the kidneys. By inhibiting the action of dehydropeptidase I, cilastatin helps maintain therapeutic levels of imipenem in the body, enhancing its antibacterial effectiveness.

Uses:

CILAPEN 250MG INJECTION is prescribed for the treatment of the following conditions:

1. Severe Infections: It is used to treat severe bacterial infections, including pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, septicemia, and infections caused by multidrug-resistant bacteria.
2. Hospital-Acquired Infections: CILAPEN 250MG INJECTION may be used to treat infections acquired in the hospital setting, including those caused by antibiotic-resistant bacteria.

Dosage and Administration:

The dosage of CILAPEN 250MG INJECTION is determined by the severity of the infection, the patient’s age, weight, and renal function, as well as the specific bacterial susceptibility. It is administered intravenously by a healthcare professional in a hospital or clinical setting. The dosage and duration of treatment should be determined by a qualified healthcare provider.

Precautions:

Before using CILAPEN 250MG INJECTION, consider the following precautions:

1. Allergies: Inform your healthcare provider if you have any known allergies to carbapenem antibiotics or any other medications.
2. Renal Impairment: Use with caution in patients with renal impairment, as dosage adjustments may be necessary based on renal function. Close monitoring of renal function is recommended during treatment.
3. Seizure Disorders: Imipenem may lower the seizure threshold, especially at higher doses or in patients with a history of seizure disorders. Use with caution in such patients and monitor for signs of neurological adverse effects.

Side Effects:

Common side effects of CILAPEN 250MG INJECTION may include:

1. Nausea and Vomiting: Some individuals may experience gastrointestinal upset, including nausea, vomiting, and diarrhea.
2. Injection Site Reactions: Pain, redness, or swelling at the injection site may occur.
3. Allergic Reactions: Serious allergic reactions, including anaphylaxis, may rarely occur. Seek immediate medical attention if you experience signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing.

Storage:

CILAPEN 250MG INJECTION should be stored at room temperature, away from moisture and heat. It should be kept out of the reach of children and pets. Unused portions of the medication should be discarded according to proper disposal guidelines.

FAQ:

1. How quickly does CILAPEN 250MG INJECTION work?
   • CILAPEN 250MG INJECTION starts to exert its antibacterial effects shortly after administration, with noticeable clinical improvement typically observed within 24 to 48 hours in most cases of bacterial infection.
2. Can CILAPEN 250MG INJECTION be used for community-acquired infections?
   • CILAPEN 250MG INJECTION is usually reserved for the treatment of severe infections, particularly those caused by multidrug-resistant bacteria, and is typically administered in a hospital setting. It may not be routinely used for community-acquired infections unless directed by a healthcare provider.
3. Are there any drug interactions with CILAPEN 250MG INJECTION?
   • Imipenem may interact with certain medications, such as valproic acid, leading to reduced serum levels of valproic acid and potentially increasing the risk of seizures. It is essential to inform your healthcare provider about all medications you are taking, including prescription, over-the-counter, and herbal products, before starting treatment with CILAPEN 250MG INJECTION.