Cinam 500mg Injection

Cinam 500mg Injection is a combination medication containing two active ingredients: Imipenem & Cilastatin. It is classified as a broad-spectrum antibiotic used for the treatment of severe bacterial infections. Imipenem is a carbapenem antibiotic, while cilastatin is a renal dehydropeptidase inhibitor that prevents the breakdown of imipenem in the kidneys, thus extending its duration of action.

Key Ingredients:

• Imipenem: Imipenem is a carbapenem antibiotic with a broad spectrum of activity against many Gram-positive and Gram-negative bacteria, including multi-drug resistant strains. It works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.
• Cilastatin: Cilastatin is a renal dehydropeptidase inhibitor that prevents the degradation of imipenem by renal enzymes. By inhibiting renal metabolism, cilastatin increases the plasma concentration of imipenem and prolongs its antibacterial activity.

Uses:

• Treatment of Severe Bacterial Infections: Cinam 500mg Injection is indicated for the treatment of severe bacterial infections caused by susceptible organisms. These infections may include complicated intra-abdominal infections, complicated urinary tract infections, lower respiratory tract infections, septicemia, and bacterial meningitis.

Administration:

• Cinam 500mg Injection is administered intravenously (into a vein) by a healthcare professional in a hospital or clinical setting.
• The dosage and duration of treatment with Cinam 500mg Injection are determined by the severity of the infection, the patient’s renal function, and the susceptibility of the causative organism.
• It is essential to complete the full course of treatment as prescribed, even if symptoms improve before the medication is finished, to prevent the development of antibiotic resistance.

Precautions:

• Cinam 500mg Injection should be used with caution in patients with a history of hypersensitivity reactions to carbapenem antibiotics or other beta-lactam antibiotics.
• Patients receiving Cinam 500mg Injection should be monitored closely for signs of allergic reactions, including rash, itching, swelling, or difficulty breathing.
• Cinam 500mg Injection may cause gastrointestinal side effects such as nausea, vomiting, diarrhea, or abdominal pain. If these symptoms are severe or persistent, medical attention should be sought.

In Conclusion:

Cinam 500mg Injection, containing the combination of Imipenem and Cilastatin, is a broad-spectrum antibiotic used for the treatment of severe bacterial infections. By inhibiting bacterial cell wall synthesis and extending the duration of action of imipenem, it provides effective therapy against a wide range of susceptible organisms.