Cubil 50mg Tablet

Cubil 50mg Tablet is a combination medication containing two active ingredients: Sacubitril & Valsartan. Sacubitril is a neprilysin inhibitor, while Valsartan is an angiotensin II receptor blocker (ARB). This tablet is prescribed for the treatment of heart failure with reduced ejection fraction (HFrEF) in adults. Sacubitril works by inhibiting neprilysin, which leads to increased levels of natriuretic peptides, while Valsartan blocks the angiotensin II receptor, resulting in vasodilation and reduced blood pressure.

Uses:

Cubil 50mg Tablet is used for the treatment of heart failure with reduced ejection fraction (HFrEF) in adults. It is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure. Sacubitril/valsartan combination therapy improves symptoms, reduces the risk of heart failure progression, and enhances overall survival in patients with HFrEF.

Dosage:

The dosage of Cubil 50mg Tablet is determined by the healthcare provider based on factors such as the patient’s medical history, renal function, and response to treatment. It is usually taken orally twice daily, with or without food. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. Patients should follow the prescribed dosage and administration instructions carefully.

Side Effects:

Common side effects associated with Cubil 50mg Tablet may include hypotension (low blood pressure), dizziness, cough, hyperkalemia (high blood potassium levels), renal impairment, and angioedema. These side effects are usually mild to moderate and may improve over time. In some cases, more serious side effects such as allergic reactions or renal failure may occur. Patients should report any adverse reactions to their healthcare provider promptly.

Precautions:

Before using Cubil 50mg Tablet, patients should inform their healthcare provider about any pre-existing medical conditions, allergies, or medications they are currently taking. This medication may interact with other drugs, so it’s essential to review the patient’s medication regimen to avoid potential interactions. Patients with a history of angioedema, hypotension, or renal impairment should use Cubil with caution.

When Not to Use:

Cubil 50mg Tablet is contraindicated in patients with a known hypersensitivity to Sacubitril, Valsartan, or any other components of the medication. It should not be used concomitantly with ACE inhibitors or within 36 hours of switching from or to an ACE inhibitor therapy. Pregnant women should avoid Cubil due to the potential risk of fetal harm.