Pacivan A 20/5mg Tablet

Pacivan A 20/5mg Tablet is a combined medication comprising two active components: Olmesartan & Amlodipine. It is formulated as an oral tablet and is primarily prescribed for managing hypertension (high blood pressure).

Active Ingredients:

1. Olmesartan: It belongs to the class of drugs known as angiotensin II receptor blockers (ARBs). Olmesartan works by inhibiting the action of angiotensin II, a substance in the body that constricts blood vessels, thereby helping blood vessels relax and dilate. This action leads to lowered blood pressure.
2. Amlodipine: This medication is classified as a calcium channel blocker (CCB). Amlodipine works by preventing the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation (relaxation of blood vessels) and decreased peripheral resistance, resulting in lowered blood pressure.

Uses:

Pacivan A 20/5mg Tablet is prescribed for:

• Managing hypertension (high blood pressure) by reducing blood pressure levels and maintaining them within a normal range.
• Its combination of Olmesartan and Amlodipine offers complementary mechanisms of action, effectively controlling blood pressure.

Mechanism of Action:

• Olmesartan: Blocks the effects of angiotensin II, leading to vasodilation and decreased blood pressure.
• Amlodipine: Inhibits calcium influx into vascular smooth muscle cells, resulting in relaxation of blood vessels and decreased peripheral resistance, thereby reducing blood pressure.

Administration:

Take Pacivan A 20/5mg Tablet orally, with or without food, as directed by your healthcare provider. The dosage may vary based on individual response and the severity of hypertension. Follow the prescribed regimen strictly and ensure regular monitoring of blood pressure levels.

Side Effects:

Common side effects of Pacivan A 20/5mg Tablet may include:

• Dizziness
• Fatigue
• Flushing
• Peripheral edema (swelling of extremities)
• Headache
• Nausea

Precautions:

• Inform your healthcare provider about any pre-existing medical conditions, including liver or kidney problems, before starting Pacivan A therapy.
• Exercise caution when performing tasks that require mental alertness, as Pacivan A may cause dizziness or lightheadedness.
• Avoid consuming grapefruit or grapefruit juice while taking Pacivan A, as it may potentiate the side effects of the medication.

Contraindications:

Pacivan A 20/5mg Tablet is contraindicated in individuals with a known hypersensitivity to Olmesartan, Amlodipine, or any tablet components. It should not be used in combination with strong CYP3A4 inhibitors and is contraindicated in patients with severe hypotension.