Protak 25mg Tablet

Protak 25mg Tablet contains Levosulpiride, a medication belonging to the class of atypical antipsychotics. It is primarily used for the management of various psychiatric disorders, including schizophrenia, bipolar disorder, and major depressive disorder. Levosulpiride exerts its therapeutic effects by modulating the activity of dopamine receptors in the brain, thereby influencing mood, behavior, and psychotic symptoms.

Uses:

• Protak 25mg Tablet is indicated for the treatment of schizophrenia, a chronic mental disorder characterized by disturbances in perception, cognition, and emotional expression.
• It may also be prescribed for the management of bipolar disorder (manic-depressive illness), a mood disorder characterized by episodes of mania (elevated mood) and depression (low mood).
• Additionally, Protak 25mg Tablet is used in the treatment of major depressive disorder (MDD), a mood disorder characterized by persistent feelings of sadness, hopelessness, and loss of interest or pleasure in daily activities.

How It Works:

• Levosulpiride acts as a selective antagonist at dopamine D2 and D3 receptors in the brain, leading to the inhibition of dopamine-mediated neurotransmission.
• By blocking dopamine receptors, Levosulpiride helps regulate abnormal dopamine activity in certain brain regions associated with psychotic symptoms, such as the mesolimbic pathway.
• Levosulpiride also exerts prokinetic effects by enhancing dopamine release in the gastrointestinal tract, which may contribute to its use in the treatment of gastrointestinal disorders such as dyspepsia and gastroparesis.

Dosage:

• The dosage of Protak 25mg Tablet should be determined by a healthcare professional based on the specific psychiatric condition being treated, the severity of symptoms, and individual patient response.
• It is usually taken orally once or twice daily, with or without food, as directed by the prescribing physician.
• The initial dosage and titration schedule may vary depending on the patient’s age, weight, renal function, and concomitant medications.

Precautions:

• Protak 25mg Tablet should be used with caution in elderly patients, as they may be more susceptible to the adverse effects of antipsychotic medications, including sedation, orthostatic hypotension, and extrapyramidal symptoms.
• It is contraindicated in patients with known hypersensitivity to Levosulpiride or any components of the formulation.
• Levosulpiride may prolong the QT interval on electrocardiogram (ECG), and caution is advised when prescribing to patients with a history of cardiac arrhythmias or concomitant use of other medications known to prolong the QT interval.

Side Effects:

Common side effects of Protak 25mg Tablet may include drowsiness, dizziness, headache, dry mouth, constipation, and weight gain. Less common but potentially serious side effects such as extrapyramidal symptoms (e.g., tremor, dystonia, akathisia), hyperprolactinemia, and neuroleptic malignant syndrome (NMS) may occur, albeit rarely.

When Not to Use:

• Protak 25mg Tablet is contraindicated in patients with a history of hypersensitivity to Levosulpiride or any components of the formulation.
• It should not be used concomitantly with medications known to prolong the QT interval or potent CYP3A4 inhibitors due to the risk of QT prolongation and potential cardiac arrhythmias.

FAQ:

1. How long does it take for Protak 25mg Tablet to work? The onset of therapeutic action may vary among individuals and depends on the specific psychiatric condition being treated. Some patients may experience symptomatic relief within a few days to weeks of initiating treatment, while others may require longer-term therapy for maximum benefit.
2. Can Protak 25mg Tablet be taken with other psychiatric medications? Levosulpiride may interact with other medications, including other antipsychotics, antidepressants, and drugs that affect dopamine neurotransmission. It is essential to inform your healthcare provider about all medications you are currently taking to avoid potential drug interactions.
3. Is Protak 25mg Tablet addictive? Levosulpiride is not considered addictive, but sudden discontinuation or abrupt withdrawal of the medication may lead to withdrawal symptoms or rebound psychiatric symptoms. It is important to follow the prescribed dosage and tapering schedule as directed by a healthcare professional.