PYROLATE INJECTION 10x1ML

PYROLATE INJECTION 10x1ML contains Glycopyrrolate as its active ingredient. It is a synthetic anticholinergic agent used to reduce salivary, tracheobronchial, and pharyngeal secretions during surgery and other medical procedures. Glycopyrrolate works by inhibiting the action of acetylcholine at muscarinic receptors in the body, leading to decreased glandular secretions.

Uses:

PYROLATE INJECTION is indicated for the following:

1. Preoperative Medication: It is administered prior to surgery to reduce salivary, tracheobronchial, and pharyngeal secretions, thereby minimizing the risk of aspiration pneumonia during anesthesia.
2. Anesthesia: It can be used during anesthesia to maintain a clear airway and improve surgical conditions by reducing excessive secretions.

Mechanism of Action:

Glycopyrrolate is a quaternary ammonium compound that acts as a competitive antagonist at muscarinic receptors in the peripheral nervous system. By blocking the action of acetylcholine, Glycopyrrolate inhibits the activity of muscarinic receptors in various organs, including salivary glands, bronchial smooth muscles, and gastrointestinal tract, resulting in decreased secretions.

Dosage and Administration:

The dosage of PYROLATE INJECTION is determined based on the patient’s age, weight, and medical condition, as well as the specific requirements of the surgical or medical procedure. It is typically administered intravenously, but may also be given intramuscularly or subcutaneously. The dose and frequency of administration should be determined by a healthcare professional.

Precautions:

1. Glaucoma: Glycopyrrolate should be used with caution in patients with narrow-angle glaucoma due to its potential to increase intraocular pressure.
2. Cardiovascular Disorders: Patients with cardiovascular diseases, such as tachycardia or cardiac arrhythmias, may be at increased risk of adverse cardiovascular effects with Glycopyrrolate administration.
3. Gastrointestinal Disorders: Glycopyrrolate may delay gastric emptying and decrease gastrointestinal motility, particularly in patients with preexisting gastrointestinal conditions.

Side Effects:

Common side effects of PYROLATE INJECTION may include dry mouth, blurred vision, urinary retention, constipation, and tachycardia. Less common adverse reactions may include flushing, palpitations, and allergic reactions. Serious adverse effects such as bronchospasm or anaphylaxis are rare but possible.

In Summary:

PYROLATE INJECTION containing Glycopyrrolate is an anticholinergic medication used to reduce secretions during surgery and anesthesia. It works by blocking muscarinic receptors, thereby decreasing glandular secretions and improving surgical conditions.