Sebivo 600mg Tablet

Sebivo 600mg Tablet contains the active ingredient telbivudine, which is an antiviral medication used in the treatment of chronic hepatitis B virus (HBV) infection. It belongs to the class of nucleoside analog reverse transcriptase inhibitors (NRTIs). Telbivudine works by inhibiting the replication of HBV, thereby reducing viral load and liver damage associated with chronic hepatitis B.

Active Ingredient:

• Telbivudine: Telbivudine is a synthetic thymidine nucleoside analog that interferes with the reverse transcription of HBV RNA into DNA. By acting as a chain terminator, telbivudine prevents the synthesis of viral DNA, leading to the suppression of HBV replication.

Mechanism of Action:

Telbivudine exerts its antiviral effects by selectively inhibiting the reverse transcriptase enzyme of hepatitis B virus. It competes with natural substrates for incorporation into the viral DNA chain, leading to premature termination of DNA synthesis and inhibition of viral replication. This ultimately reduces the viral load and slows down the progression of liver disease.

Uses:

Sebivo 600mg Tablet is indicated for the treatment of chronic hepatitis B infection in adults with evidence of active viral replication and liver inflammation. It is not recommended for patients with HIV/HBV co-infection or decompensated liver disease.

Dosage and Administration:

The recommended dosage of Sebivo 600mg Tablet is 600mg taken orally once daily with or without food. The duration of treatment may vary depending on the individual patient’s response to therapy and the severity of liver disease. It is important to adhere to the prescribed dosage and regimen to achieve optimal treatment outcomes.

Side Effects:

Common side effects of Sebivo 600mg Tablet may include:

• Headache
• Fatigue
• Nausea
• Diarrhea
• Dizziness
• Elevated liver enzymes
• Myopathy (muscle weakness or pain)
• Peripheral neuropathy (tingling or numbness in the hands or feet)

Precautions:

• Sebivo should be used with caution in patients with pre-existing renal impairment or myopathy.
• Regular monitoring of liver function tests and creatine kinase levels is recommended during treatment with telbivudine.
• Patients should be advised to report any signs of muscle weakness, neuropathy, or worsening liver function to their healthcare provider.
• Sebivo may cause fetal harm if used during pregnancy, and effective contraception should be used by both male and female patients during treatment.

Conclusion:

Sebivo 600mg Tablet containing telbivudine is an effective antiviral medication used for the treatment of chronic hepatitis B infection in adults. By inhibiting viral replication, telbivudine helps suppress HBV replication and reduce liver inflammation, thereby improving liver function and clinical outcomes in patients with chronic hepatitis B.