Sofvel 400/100mg Tablet

Sofvel 400/100mg Tablet combines two potent antiviral medications, Sofosbuvir & Velpatasvir, in a single formulation. Sofosbuvir belongs to the class of nucleotide analog NS5B polymerase inhibitors, while Velpatasvir is an NS5A inhibitor. This combination offers a powerful and comprehensive approach to treating chronic Hepatitis C virus (HCV) infections, targeting different stages of the viral replication cycle and providing a high barrier to resistance.

Uses:

Sofvel 400/100mg Tablet is indicated for the treatment of chronic HCV infections in adults. It is effective against multiple genotypes of the virus and is often used as a first-line therapy due to its high efficacy and tolerability. Sofvel is typically prescribed for a specified duration, leading to sustained virologic response (SVR) rates, which indicate the cure of HCV infection.

Side Effects:

While Sofvel 400/100mg Tablet is generally well-tolerated, some individuals may experience the following side effects:

1. Fatigue: Feeling tired or lethargic.
2. Headache: Mild to moderate headaches may occur.
3. Nausea: Some individuals may experience gastrointestinal discomfort or nausea.
4. Insomnia: Difficulty sleeping or disturbances in sleep patterns.
5. Anemia: A decrease in red blood cell count, which may cause weakness or fatigue.

Precautions:

To ensure safe and effective use of Sofvel 400/100mg Tablet, consider the following precautions:

1. Liver Function: Regular monitoring of liver function is recommended, especially in patients with pre-existing liver disease.
2. Drug Interactions: Inform your healthcare provider about all medications you are taking, as Sofvel may interact with certain drugs, including other antivirals and medications metabolized by the liver.
3. Pregnancy and Breastfeeding: Use of Sofvel during pregnancy or breastfeeding should be carefully considered, and the potential risks weighed against the benefits.
4. HIV Coinfection: Sofvel may be used in patients coinfected with HIV and HCV, but close monitoring is necessary due to potential drug interactions and effects on HIV viral load.
5. Adherence: It is essential to take Sofvel exactly as prescribed, without missing doses, to maximize treatment efficacy and reduce the risk of viral resistance.

Contraindications:

Sofvel 400/100mg Tablet is contraindicated in individuals with a known hypersensitivity to Sofosbuvir, Velpatasvir, or any of the tablet’s components.