Uperio 50mg 24/26mg Tablet

Uperio 50mg 24/26mg Tablet contains a combination of two active ingredients: Sacubitril & Valsartan. This medication is primarily used to treat heart failure by improving symptoms and reducing the risk of hospitalization for heart failure.

Uses:

• Heart Failure: Uperio is indicated for the treatment of heart failure with reduced ejection fraction (HFrEF). It works by blocking certain enzymes that can lead to increased levels of harmful substances in the body, thereby helping to improve heart function and reduce the risk of heart failure-related complications.

Side Effects:

• Common side effects of Uperio may include dizziness, low blood pressure (hypotension), cough, diarrhea, and increased levels of potassium in the blood (hyperkalemia).
• Serious side effects may include angioedema (swelling of the face, lips, tongue, or throat), kidney problems, and low white blood cell count (neutropenia).
• Seek immediate medical attention if you experience symptoms of a severe allergic reaction, such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

Precautions:

• Before taking Uperio, inform your healthcare provider about any pre-existing medical conditions, including kidney or liver problems, electrolyte imbalances, or a history of angioedema.
• Use caution when driving or operating machinery, as Uperio may cause dizziness or lightheadedness.
• Avoid alcohol while taking Uperio, as it may worsen certain side effects such as dizziness or low blood pressure.

When Not to Use:

• Do not take Uperio if you have a known allergy to sacubitril, valsartan, or any other ingredients in the medication.
• Uperio is contraindicated in patients who are pregnant, as it may cause harm to the developing fetus. It is also contraindicated in patients with a history of angioedema related to previous ACE inhibitor or ARB therapy.

FAQ:

1. What is the recommended dosage of Uperio?
   • The recommended starting dose of Uperio is 49/51 mg (sacubitril/valsartan) twice daily. Your healthcare provider may adjust the dosage based on your individual response and tolerability.
2. How does Uperio work to treat heart failure?
   • Sacubitril in Uperio inhibits the enzyme neprilysin, which leads to increased levels of beneficial peptides that help widen blood vessels and reduce sodium and water retention. Valsartan blocks the action of angiotensin II, a hormone that narrows blood vessels and increases blood pressure, thereby reducing the workload on the heart.
3. Can Uperio be used in combination with other heart failure medications?
   • Uperio may be used in combination with other heart failure medications, such as beta-blockers, diuretics, and mineralocorticoid receptor antagonists, as prescribed by your healthcare provider.
4. How long does it take to see the effects of Uperio in treating heart failure?
   • The effects of Uperio on heart failure symptoms may vary from person to person. Some individuals may experience improvement in symptoms within weeks of starting treatment, while others may require longer-term therapy to achieve optimal benefits.
5. Are there any dietary restrictions while taking Uperio?
   • While taking Uperio, it is essential to follow a heart-healthy diet low in sodium and saturated fats and rich in fruits, vegetables, and whole grains. Avoid excessive intake of salt and high-potassium foods unless otherwise advised by your healthcare provider.