VILGET M 50/1000MG TABLET

VILGET M 50/1000MG TABLET is a combination medication used for the management of type 2 diabetes mellitus. It contains two active ingredients: Vildagliptin & Metformin, each playing a complementary role in controlling blood sugar levels.

• Vildagliptin (50 mg) is a DPP-4 (Dipeptidyl Peptidase-4) inhibitor, which works by increasing the levels of incretin hormones in the body. These hormones help regulate insulin and glucagon secretion, thus promoting lower blood sugar levels after meals.
• Metformin (1000 mg) is a biguanide that helps lower blood sugar by improving insulin sensitivity, reducing hepatic glucose production (the liver’s production of glucose), and enhancing glucose uptake by muscle cells.

This dual-action formulation makes VILGET M a highly effective treatment option for individuals with type 2 diabetes, especially those who are unable to achieve adequate blood sugar control through diet and exercise alone.

Uses:

1. Management of Type 2 Diabetes Mellitus: VILGET M is primarily used for improving glycemic control in adults with type 2 diabetes, particularly when diet, exercise, and lifestyle changes alone do not result in adequate blood sugar control.
2. Combination Therapy: It is used when metformin alone is insufficient in controlling blood glucose levels, and a second agent like Vildagliptin is needed to provide better control.
3. Weight Management: Unlike some other diabetic medications, metformin typically does not cause weight gain and may even help with modest weight loss, making it a preferred option for overweight or obese individuals with diabetes.

Side Effects:

While VILGET M is generally well-tolerated, some side effects may occur. These can include:

• Common Side Effects:
  • Gastrointestinal issues: Nausea, vomiting, diarrhea, or abdominal discomfort are common when starting Metformin. These symptoms often subside as the body adjusts.
  • Hypoglycemia (Low Blood Sugar): Although Vildagliptin and Metformin are not usually associated with causing significant hypoglycemia on their own, low blood sugar can occur when taken in combination with other anti-diabetic agents like sulfonylureas or insulin.
• Serious Side Effects:
  • Lactic Acidosis: A rare but serious complication of Metformin, lactic acidosis is a buildup of lactic acid in the blood, which can be life-threatening. Symptoms include weakness, unusual muscle pain, trouble breathing, dizziness, or cold skin.
  • Pancreatitis: Vildagliptin has been associated with an increased risk of pancreatitis, though this is relatively uncommon. Symptoms of pancreatitis include severe abdominal pain, vomiting, and nausea.
  • Kidney Issues: Both Metformin and Vildagliptin require dose adjustments in people with kidney problems. Severe kidney impairment increases the risk of both medications causing complications.

Precautions:

• Kidney Function: Both Vildagliptin and Metformin can affect kidney function. Kidney function tests should be performed regularly before and during treatment, especially in elderly patients or those with pre-existing renal conditions.
• Liver Disease: Use cautiously in patients with liver problems, as it may increase the risk of side effects.
• Lactic Acidosis Risk: Patients with conditions that increase the risk of lactic acidosis (e.g., severe dehydration, infection, alcohol consumption) should not use Metformin. If symptoms of lactic acidosis appear, seek medical attention immediately.
• Heart Disease and Stroke: Those with a history of heart disease or stroke should consult their doctor, as there may be an increased risk of complications.
• Surgery: If you are undergoing surgery or any major medical procedure, you may need to temporarily stop taking VILGET M due to the potential impact on kidney function and the risk of lactic acidosis.

When Not to Use:

• Allergy: Do not use VILGET M if you are allergic to Vildagliptin, Metformin, or any of the other ingredients in the tablet.
• Severe Kidney Impairment: If you have severe kidney dysfunction (e.g., eGFR < 30 mL/min), you should not take this medication.
• Severe Liver Disease: Those with severe liver conditions should avoid VILGET M due to potential liver-related side effects.
• Acidosis and Dehydration: If you are dehydrated or have a history of lactic acidosis, this drug is contraindicated.

FAQ:

1. How should I take VILGET M 50/1000 mg Tablet?
Take VILGET M exactly as prescribed by your doctor, typically with meals to reduce gastrointestinal side effects. Do not take more or less than the prescribed dose, and never stop taking it without consulting your healthcare provider.

2. Can I take VILGET M if I am pregnant or breastfeeding?
VILGET M is generally not recommended during pregnancy, as it may harm the fetus. If you are pregnant or planning to become pregnant, consult your doctor to discuss alternative treatment options. It is also not recommended during breastfeeding.

3. Can VILGET M cause low blood sugar (hypoglycemia)?
VILGET M alone is not likely to cause significant hypoglycemia. However, if used in combination with other anti-diabetic medications such as insulin or sulfonylureas, the risk of hypoglycemia may increase. Symptoms of low blood sugar include shakiness, sweating, confusion, and dizziness.

4. How often should I have my blood sugar tested while on VILGET M?
Regular monitoring of blood glucose levels is essential while taking VILGET M to ensure it is effectively controlling your blood sugar. Your doctor will guide you on how often you should check your blood sugar levels based on your individual condition.

5. What should I do if I miss a dose?
If you miss a dose of VILGET M, take it as soon as you remember, unless it is almost time for your next dose. Do not take two doses at once to make up for a missed dose.

6. What are the potential signs of lactic acidosis?
Lactic acidosis is a rare but serious condition associated with Metformin. Symptoms may include unusual muscle pain or weakness, breathing difficulties, dizziness, extreme fatigue, and cold skin. If you experience any of these, seek medical attention immediately.

7. Can I drink alcohol while taking VILGET M?
Excessive alcohol consumption is not recommended while taking Metformin, as it can increase the risk of lactic acidosis and may interfere with blood sugar control. Always consult your doctor before consuming alcohol.