Migrex Tablet

Migrex Tablet contains the active ingredient Flunarizine. It is a medication primarily used for the prevention of migraine headaches and associated symptoms.

Uses:

1. Migraine Prophylaxis: Migrex Tablet is prescribed for the prevention of migraine attacks in patients with recurrent migraine headaches.
2. Vertigo: It may also be used for the treatment of vertigo and other vestibular disorders.

Mechanism of Action:

Flunarizine exerts its therapeutic effects by blocking calcium channels, which helps stabilize neuronal membranes and modulate neurotransmitter release. By reducing neuronal excitability and vasodilation, Flunarizine helps prevent the initiation of migraine attacks and reduces the frequency and severity of symptoms.

Dosage and Administration:

• The recommended dosage of Migrex Tablet is determined by the healthcare provider based on the patient’s age, medical history, and the severity of migraine symptoms.
• It is usually taken orally once daily, preferably in the evening to minimize the risk of drowsiness.
• The dosage regimen may vary depending on the individual patient’s response to treatment.

Side Effects:

Common side effects of Flunarizine therapy may include drowsiness, dizziness, fatigue, weight gain, gastrointestinal disturbances (such as nausea or diarrhea), and extrapyramidal symptoms (such as tremor or dyskinesia). These side effects are usually mild and transient. However, serious side effects such as depression or movement disorders may occur rarely.

Precautions:

• Patients taking Migrex Tablet should be advised to avoid activities requiring mental alertness, such as driving or operating machinery, until they know how the medication affects them.
• Flunarizine may interact with certain medications, such as other central nervous system depressants or antihypertensive agents. It is important to inform the healthcare provider about all medications being taken.
• Abrupt discontinuation of Flunarizine may lead to rebound migraine headaches. Therefore, the dosage should be tapered gradually under medical supervision if discontinuation is necessary.

When Not to Use: Migrex Tablet should not be used in patients with a known hypersensitivity to Flunarizine or any of its components. It is also contraindicated in patients with severe depression, Parkinson’s disease, or a history of movement disorders.

FAQs:

1. How long does it take for Migrex to start working? Flunarizine may take several weeks to months of continuous treatment to achieve optimal migraine prevention. Patients may notice a reduction in the frequency and severity of migraine attacks over time.
2. Can Migrex be used during pregnancy or breastfeeding? The use of Flunarizine during pregnancy or breastfeeding should be carefully evaluated by a healthcare provider, weighing the potential risks and benefits for the mother and fetus or infant.
3. Can Migrex cause weight gain? Weight gain is a common side effect of Flunarizine therapy. Patients should be advised to monitor their weight and dietary habits while taking the medication.
4. Is Migrex addictive? Flunarizine is not addictive and does not cause dependence or withdrawal symptoms.
5. Can Migrex be used in children? Flunarizine is not recommended for use in children under 18 years of age due to limited safety and efficacy data in this population.