Trihexyphenidyl, also known as benzhexol, blocks acetylcholine in the brain to rebalance it against dopamine. That helps tremor and stiffness, particularly the movement side effects caused by antipsychotic medicines.

What Trihexyphenidyl Is Used For

  • Stiffness, tremor and restlessness caused by antipsychotic medicines
  • Parkinson disease, mainly for tremor
  • Excess drooling in some conditions
  • Certain dystonias

Common Side Effects

  • Dry mouth
  • Blurred vision
  • Constipation
  • Confusion or memory problems, particularly in older adults

Precautions

It is not suitable in glaucoma or with difficulty passing urine from an enlarged prostate. Older adults are much more prone to confusion, falls and memory problems with this class. Do not stop it abruptly after long use. It is sometimes misused, so it should be taken only as prescribed and kept securely.

This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.