Colchicine reduces the inflammation that uric acid crystals cause inside a joint. It does not lower uric acid itself, so it treats and prevents attacks while a separate medicine such as allopurinol deals with the underlying level.

What Colchicine Is Used For

Acute gout attacks
Preventing attacks when starting uric acid lowering treatment
Familial Mediterranean fever
Pericarditis, on specialist advice

Common Side Effects

Loose motions, the earliest and most common effect
Nausea and vomiting
Abdominal cramps
Muscle weakness with long term use

Precautions

Diarrhoea is the signal that the amount is too high, and continuing past it is dangerous. Colchicine is toxic in overdose, so never exceed what your doctor prescribed and keep it away from children. Doses are reduced in kidney and liver disease. It interacts with clarithromycin, some antifungals and statins, so mention it before starting any new medicine.

This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.