Amisulpride acts selectively on dopamine receptors. At higher doses it treats the hallucinations and disordered thinking of psychosis, and at low doses it is sometimes used for the withdrawal and flatness that can accompany it.

What Amisulpride Is Used For

Schizophrenia, both acute episodes and maintenance
Predominantly negative symptoms, at lower doses
Severe nausea and vomiting, in some low dose formulations

Common Side Effects

Raised prolactin, causing breast tenderness, milk discharge or period changes
Trouble sleeping or drowsiness
Stiffness, tremor or restlessness
Weight gain

Precautions

It is cleared by the kidneys, so the dose is reduced in kidney disease. It can affect the heart rhythm, and an ECG may be advised, particularly with other medicines that do the same. Report severe stiffness with fever, uncontrolled facial movements, or fainting straight away. Do not stop it because you feel well, since relapse risk rises sharply.

This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.