Acoid Tablets 5/190/12.5

Acoid Tablets 5/190/12.5 is a medication available in tablet form that combines three active ingredients: amlodipine, valsartan, & hydrochlorothiazide. This combination medication is commonly used to treat hypertension (high blood pressure) by addressing multiple factors contributing to elevated blood pressure levels.

Active Ingredients:

Acoid Tablets 5/190/12.5 contains:

• Amlodipine: Amlodipine belongs to a class of medications called calcium channel blockers, which work by relaxing and dilating blood vessels, thereby reducing blood pressure.
• Valsartan: Valsartan is an angiotensin II receptor antagonist, which blocks the action of angiotensin II, a hormone that causes blood vessels to narrow. By blocking angiotensin II receptors, valsartan helps to relax blood vessels and lower blood pressure.
• Hydrochlorothiazide: Hydrochlorothiazide is a thiazide diuretic that works by increasing urine production, leading to the removal of excess fluid and salt from the body. This helps to reduce blood volume and lower blood pressure.

Uses:

Acoid Tablets 5/190/12.5 is indicated for the treatment of hypertension (high blood pressure). By combining three different classes of medications with complementary mechanisms of action, it provides more effective blood pressure control compared to single-drug therapy.

Mechanism of Action:

• Amlodipine: Amlodipine inhibits the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and decreased peripheral vascular resistance.
• Valsartan: Valsartan blocks the binding of angiotensin II to its receptors, preventing vasoconstriction and aldosterone secretion, resulting in vasodilation and decreased blood pressure.
• Hydrochlorothiazide: Hydrochlorothiazide increases urinary excretion of sodium and water by inhibiting the reabsorption of sodium in the distal tubules of the kidneys, leading to reduced blood volume and decreased blood pressure.

Administration:

Acoid Tablets 5/160/12.5 should be taken orally with water, as directed by a healthcare professional. It is usually recommended to be taken once daily, preferably in the morning, with or without food. The dosage may vary depending on individual patient factors and blood pressure response.

Side Effects:

Common side effects associated with Acoid Tablets 5/160/12.5 may include:

• Dizziness
• Headache
• Fatigue
• Edema (swelling)
• Hypotension (low blood pressure)

Precautions:

Before using Acoid Tablets 5/160/12.5, patients should be aware of the following precautions:

• Inform healthcare providers about any known allergies to amlodipine, valsartan, hydrochlorothiazide, or other medications.
• Monitor blood pressure regularly to ensure optimal control and adjust dosage as needed.
• Use caution in patients with kidney or liver impairment, electrolyte imbalances, or diabetes mellitus.

Contraindications:

Acoid Tablets 5/190/12.5 is contraindicated in patients with:

• Known hypersensitivity to any of the components of the medication.
• History of angioedema related to previous treatment with angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs).
• Severe renal impairment (creatinine clearance <30 mL/min) or anuria.