About this product
Overview
Bestrix 250mg IV Injection contains the active ingredient Ceftriaxone, which belongs to the class of antibiotics known as cephalosporins. It is a broad-spectrum antibiotic used for the treatment of bacterial infections caused by susceptible organisms. Ceftriaxone is administered intravenously and is effective against a wide range of bacteria, including those that cause respiratory, urinary tract, skin, and soft tissue infections, as well as meningitis and septicemia.
Uses
- Bestrix 250mg IV Injection is indicated for the treatment of various bacterial infections caused by susceptible organisms.
- It may be prescribed for conditions such as community-acquired pneumonia, urinary tract infections, skin and soft tissue infections, septicemia, meningitis, and other serious bacterial infections.
- Ceftriaxone is particularly useful for infections caused by multidrug-resistant bacteria or in situations where oral antibiotics may not be effective or feasible.
How It Works
Ceftriaxone works by interfering with the synthesis of bacterial cell walls, leading to cell death and bacterial lysis. It exerts its bactericidal effects by binding to penicillin-binding proteins (PBPs) on the bacterial cell membrane, thereby inhibiting the final transpeptidation step of peptidoglycan synthesis in the bacterial cell wall.
Dosage
- The dosage of Bestrix 250mg IV Injection should be determined by a healthcare professional based on the severity of the infection, the patient’s age and weight, renal function, and other factors.
- It is typically administered intravenously over a period of 30 minutes to 2 hours, depending on the specific indication and patient’s condition.
Precautions
- Use Bestrix 250mg IV Injection with caution in patients with a history of hypersensitivity reactions to cephalosporins or other beta-lactam antibiotics.
- Monitor renal function regularly, especially in patients with impaired renal function or those receiving high doses of ceftriaxone or prolonged treatment duration.
- Do not use Bestrix 250mg IV Injection in patients with a history of severe allergic reactions (anaphylaxis) to beta-lactam antibiotics such as penicillins or cephalosporins.
Side Effects
Common side effects of Bestrix 250mg IV Injection may include diarrhea, nausea, vomiting, abdominal pain, rash, headache, and injection site reactions. Serious side effects such as allergic reactions, Clostridium difficile-associated diarrhea, and renal impairment may occur rarely.
When Not to Use
- Do not use Bestrix 250mg IV Injection in patients with a history of severe allergic reactions (anaphylaxis) to cephalosporins or other beta-lactam antibiotics.
- It is contraindicated in patients with a history of cholestatic jaundice or hepatic dysfunction associated with ceftriaxone use.
Substitutes for Bestrix 250mg IV Injection
These medicines contain the same salt as Bestrix 250mg IV Injection (Ceftriaxone 250mg), so they are common substitutes. Compare their prices, and change brands only after checking with your doctor or pharmacist.
| Medicine | Manufacturer | Pack | Price |
|---|---|---|---|
| Traxon 250mg IM Injection | Glaxo Smithkline | 1'S | Rs 127.71 |
| Sporex 250mg injection | Raazee Therapeutics | 1 Vial injection | Rs 146.02 |
| Traxon 250mg IV Injection | Glaxo Smithkline | 1 S | Rs 161.38 |
| Zeftrox 250mg injection | Zafa Pharmaceutical Labortories | 1 Vial injection | Rs 196.56 |
| Eftriax 250mg injection | Pharmatec | 1 Vial injection | Rs 224.64 |
| Zocef 250mg injection | Nexus | 1 Vial injection | Rs 224.64 |
| Hiway 250mg injection | Mass Pharma | 1 Vial injection | Rs 224.64 |
| Total 250mg injection | Wise Pharma | 1 Vial injection | Rs 242.40 |
Other strengths of Ceftriaxone
| Medicine | Manufacturer | Strength | Price |
|---|---|---|---|
| Traxon 500mg Injection | Glaxo Smithkline | 500mg | Rs 214.94 |
| Neogine 500 mg IV Injection | AGP Pharmacuticals | 500mg | Rs 224.26 |
| Neogine 500 mg IM Injection | AGP Pharmacuticals | 500mg | Rs 224.26 |
| Traxon 500mg IV Injection | Glaxo Smithkline | 500mg | Rs 252.88 |
See all brands and prices on our Ceftriaxone page.
Frequently asked questions
How long does it take for Bestrix 250mg IV Injection to work?
The onset of action of Bestrix 250mg IV Injection varies depending on the type and severity of the infection. Improvement in symptoms may be observed within 24 to 48 hours of starting treatment.
Can Bestrix 250mg IV Injection be given to pregnant women?
Bestrix 250mg IV Injection may be used in pregnant women if the potential benefits outweigh the risks. However, it should be used with caution and only if clearly needed, as safety data in pregnant women are limited.
Is Bestrix 250mg IV Injection safe for children?
Bestrix 250mg IV Injection may be used in children under the supervision of a healthcare professional. The dosage should be adjusted based on the child’s age, weight, and the severity of the infection.
This information is for general awareness only. It does not replace advice from your doctor or pharmacist. Always read the leaflet and follow the directions you were given.
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