Pharmatrexate 50mg Injection

Pharmatrexate 50mg Injection contains the active ingredient Methotrexate, which belongs to the class of medications known as antimetabolites. It is used to treat various conditions, including cancer, autoimmune diseases, and certain inflammatory conditions.

Uses:

Pharmatrexate 50mg Injection is primarily prescribed for the following conditions:

• Cancer: Methotrexate is used in the treatment of various cancers, including leukemia, lymphoma, and certain solid tumors.
• Rheumatoid Arthritis: Methotrexate is often used to reduce inflammation and slow the progression of rheumatoid arthritis.
• Psoriasis: Methotrexate is effective in treating severe cases of psoriasis, a chronic skin condition characterized by red, scaly patches.
• Autoimmune Diseases: Methotrexate may be used to treat autoimmune diseases such as lupus, vasculitis, and inflammatory bowel disease.

Mechanism of Action:

Methotrexate works by inhibiting the enzyme dihydrofolate reductase, which is involved in the synthesis of DNA, RNA, and proteins. By interfering with these processes, methotrexate inhibits the growth and proliferation of rapidly dividing cells, including cancer cells and cells involved in the immune response.

Administration:

Pharmatrexate 50mg Injection is administered by injection into a muscle or vein, as directed by your healthcare provider. The dosage and frequency of administration depend on the condition being treated and the patient’s response to treatment.

Side Effects:

Common side effects of Pharmatrexate 50mg Injection may include nausea, vomiting, diarrhea, mouth sores, and hair loss. Serious side effects may include bone marrow suppression, liver toxicity, and lung problems. It is important to report any unusual or severe side effects to your healthcare provider.

Precautions:

• Inform your healthcare provider about any pre-existing medical conditions, especially liver or kidney problems.
• Disclose all medications, including prescription and over-the-counter drugs, as well as any herbal supplements, to avoid potential interactions.
• Use effective contraception during treatment, as methotrexate may cause harm to an unborn baby.

When Not to Use:

Pharmatrexate 50mg Injection may not be suitable for use in individuals with known hypersensitivity or allergy to methotrexate or any components of the injection. It is contraindicated in pregnant women and patients with severe liver or kidney impairment.