UROGRAFIN 76% 100ML

UROGRAFIN 76% 100ML is a diagnostic imaging agent used primarily for urography procedures. It contains the active ingredient hexaminolevulinate, which is a contrast medium used to enhance the visualization of the urinary tract during radiographic examinations. UROGRAFIN 76% 100ml is administered via intravenous injection or as an oral solution, depending on the specific imaging protocol and patient requirements.

Active Ingredient:

Hexaminolevulinate: Hexaminolevulinate is a contrast agent that enhances the visibility of the urinary system during radiographic imaging. It is a water-soluble compound that absorbs X-rays, thereby increasing the contrast between the urinary tract structures and surrounding tissues.

Mechanism of Action:

Hexaminolevulinate functions by selectively accumulating in the renal tubules and urinary bladder following administration. Upon exposure to X-rays during radiographic imaging, hexaminolevulinate absorbs the radiation and attenuates the X-rays, resulting in enhanced visualization of the urinary system structures. This enables healthcare providers to obtain detailed images of the kidneys, ureters, bladder, and associated structures.

Uses:

UROGRAFIN 76% 100ml is indicated for use in various diagnostic imaging procedures, including:

• Urography: It is commonly used to visualize the urinary tract, including the kidneys, ureters, and bladder, to diagnose conditions such as urinary tract infections, kidney stones, and structural abnormalities.
• Cystography: UROGRAFIN 76% 100ml may be employed in cystography to assess bladder function and detect abnormalities such as urinary reflux or bladder tumors.

Dosage and Administration:

The dosage and administration of UROGRAFIN 76% 100ml depend on the specific imaging protocol, patient factors, and the discretion of the prescribing healthcare provider. It is typically administered via intravenous injection or as an oral solution, with the dosage tailored to the individual patient’s needs and the imaging requirements.

Side Effects:

Common side effects associated with UROGRAFIN 76% 100ml may include:

• Nausea
• Vomiting
• Flushing
• Headache
• Allergic reactions (rare)
• Injection site reactions (if administered intravenously)

Precautions:

• Patients with a known hypersensitivity to hexaminolevulinate or other contrast agents should avoid its use.
• Adequate hydration before and after contrast administration may help minimize the risk of adverse effects, particularly in patients with renal impairment.
• Special precautions should be taken in patients with a history of asthma, allergies, or renal dysfunction.
• Pregnant or breastfeeding women should consult their healthcare provider before undergoing imaging procedures involving UROGRAFIN 76% 100ml.

Conclusion:

UROGRAFIN 76% 100ml is a diagnostic imaging agent containing hexaminolevulinate, utilized for urography procedures to visualize the urinary tract structures. When used under the supervision of healthcare professionals and following appropriate safety protocols, UROGRAFIN 76% 100ml can provide valuable diagnostic information while minimizing the risk of adverse effects.