Viread 300mg Tablet contains the active ingredient Tenofovir Disoproxil, which is a nucleotide reverse transcriptase inhibitor (NRTI). It is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. Tenofovir Disoproxil works by blocking the activity of reverse transcriptase, an enzyme that is essential for the replication of HIV and HBV. This medication helps to reduce viral load, slow down disease progression, and improve liver function in patients with HBV infection.
Uses:
- HIV Infection: Viread 300mg Tablet is indicated for the treatment of HIV infection in combination with other antiretroviral medications. It helps to suppress viral replication, reduce HIV viral load, and improve immune function, thereby delaying the progression of HIV to acquired immunodeficiency syndrome (AIDS).
- Chronic Hepatitis B Virus (HBV) Infection: Tenofovir Disoproxil is also used in the treatment of chronic HBV infection. It helps to suppress HBV replication, reduce liver inflammation, and lower the risk of developing complications such as liver cirrhosis and hepatocellular carcinoma (liver cancer).
Side Effects:
While Viread 300mg Tablet is generally well-tolerated, it may cause side effects in some individuals. Common side effects associated with Tenofovir Disoproxil include:
- Nausea and Vomiting: Some patients may experience nausea and vomiting, particularly at the beginning of treatment. Taking the medication with food can help alleviate these symptoms.
- Diarrhea: Diarrhea is a common side effect of Tenofovir Disoproxil and may occur in some individuals. Maintaining adequate hydration and dietary adjustments can help manage diarrhea.
- Fatigue: Fatigue or weakness may occur during treatment with Viread 300mg Tablet. Getting adequate rest and maintaining a healthy lifestyle can help manage fatigue.
- Renal Toxicity: Long-term use of Tenofovir Disoproxil may lead to renal toxicity, including kidney dysfunction and reduced kidney function. Patients should undergo regular monitoring of renal function while taking this medication.
Precautions:
- Bone Health: Tenofovir Disoproxil may cause bone loss or decrease bone mineral density, particularly with long-term use. Patients should ensure an adequate intake of calcium and vitamin D and discuss bone health with their healthcare provider.
- HIV Resistance: Patients with HIV infection should take Viread 300mg Tablet as part of a combination regimen to reduce the risk of developing drug resistance.
- Pregnancy and Breastfeeding: The safety of Tenofovir Disoproxil during pregnancy and breastfeeding is not well-established. Pregnant or breastfeeding women should consult their healthcare provider before using this medication.
- Liver Dysfunction: Patients with severe liver impairment should use Viread 300mg Tablet with caution, as dosage adjustments may be necessary. Close monitoring of liver function is recommended during treatment.
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