Zoledronic acid is a medication used in the treatment of osteoporosis, bone metastases, and hypercalcemia of malignancy. It belongs to a class of drugs called bisphosphonates.

Zoledronic acid works by inhibiting the activity of osteoclasts, which are cells responsible for breaking down bone tissue. By slowing down bone resorption, zoledronic acid helps to increase bone density, reduce the risk of fractures, and manage conditions such as osteoporosis and bone metastases