Hiloric 80mg Tablet

Hiloric 80mg Tablet contains Febuxostat, a medication primarily used for the long-term management of hyperuricemia (elevated uric acid levels in the blood) in patients with gout. Gout is a type of arthritis characterized by sudden, severe attacks of pain, redness, and swelling in joints, often occurring in the big toe. Febuxostat, the active ingredient in Hiloric 80mg, is a potent xanthine oxidase inhibitor. This enzyme plays a critical role in the production of uric acid in the body. By inhibiting xanthine oxidase, Hiloric 80mg effectively reduces uric acid levels, thereby helping to prevent gout flares and other complications associated with hyperuricemia.

Uses of Hiloric 80mg Tablet

1. Gout Management: Hiloric 80mg is primarily used to manage chronic gout by reducing uric acid levels, preventing the recurrence of gout attacks, and managing tophi, which are deposits of uric acid crystals in joints and tissues.
2. Hyperuricemia: This medication is prescribed to manage chronic hyperuricemia, especially in conditions where there is excessive production or decreased excretion of uric acid, such as in Lesch-Nyhan syndrome.
3. Kidney Stones Prevention: Hiloric 80mg may also be used to prevent the formation of kidney stones in patients who have elevated uric acid levels in their urine.

Side Effects

As with any medication, Hiloric 80mg can cause side effects, although not everyone will experience them. Common side effects include:

1. Liver Function Abnormalities: Elevated liver enzymes are a relatively common side effect and should be monitored through regular blood tests.
2. Gastrointestinal Issues: Patients may experience nausea, diarrhea, or abdominal discomfort.
3. Skin Reactions: Skin rashes and itching are possible. Rarely, severe skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis may occur.
4. Cardiovascular Risks: There is a potential risk of cardiovascular events such as heart attacks or strokes, particularly in patients with a history of heart disease.
5. Gout Flares: During the initial phase of treatment, some patients may experience gout flares as the body adjusts to the lowering of uric acid levels.

Precautions

1. Liver Function Monitoring: Regular liver function tests are recommended during treatment, as Hiloric 80mg can cause elevations in liver enzymes.
2. Cardiovascular Precautions: Patients with a history of cardiovascular disease should use Hiloric 80mg with caution due to the potential risk of heart-related events.
3. Pregnancy and Breastfeeding: This medication should be used during pregnancy or breastfeeding only if absolutely necessary, as the effects on the fetus or infant are not fully known.
4. Kidney Function: Patients with severe kidney impairment may require dose adjustments, and regular monitoring of kidney function is advised.
5. Drug Interactions: Febuxostat can interact with medications such as azathioprine, mercaptopurine, and theophylline, leading to serious side effects. Always inform your doctor about all the medications you are taking.

When Not to Use Hiloric 80mg Tablet

1. Hypersensitivity: Do not use Hiloric 80mg if you are allergic to Febuxostat or any other components of the tablet.
2. Severe Cardiovascular Disease: Avoid use in patients with severe cardiovascular conditions without close medical supervision.
3. Concurrent Use with Certain Medications: Avoid using Hiloric 80mg in combination with medications like azathioprine or mercaptopurine due to the risk of toxicity.

Frequently Asked Questions (FAQs)

1. How long does it take for Hiloric 80mg to work?
   • It may take several weeks to months for Hiloric 80mg to significantly lower uric acid levels and prevent gout flares. Continuous use is usually required for long-term management.
2. Can Hiloric 80mg be used during a gout flare-up?
   • Hiloric 80mg is not typically used to treat an acute gout flare but rather to prevent future flares. Consult your doctor for appropriate medications during an acute attack.
3. Is long-term use of Hiloric 80mg safe?
   • Hiloric 80mg can be used long-term under medical supervision. Regular monitoring of liver and kidney function is essential.
4. What should I avoid while taking Hiloric 80mg?
   • It is advisable to limit alcohol consumption, avoid high-purine foods (like red meat and seafood), and maintain a healthy diet to help control uric acid levels.
5. Can I stop taking Hiloric 80mg if I feel better?
   • You should not stop taking Hiloric 80mg without consulting your doctor, even if your symptoms improve, as stopping suddenly can lead to a recurrence of hyperuricemia and gout attacks.