Febstat 40mg Tablet contains Febuxostat as its active ingredient. It belongs to the class of medications known as xanthine oxidase inhibitors and is primarily used to treat hyperuricemia (elevated uric acid levels) in patients with gout. Febuxostat works by inhibiting the enzyme xanthine oxidase, thereby reducing the production of uric acid in the body. This tablet form allows for convenient oral administration.
Uses:
- Gout: Febstat 40mg Tablet is indicated for the management of hyperuricemia in patients with gout, a condition characterized by the deposition of urate crystals in the joints, leading to inflammation and pain.
- Hyperuricemia: It may also be prescribed to lower uric acid levels in patients with elevated serum urate levels due to various other causes, such as renal impairment or certain medications.
Side Effects:
Common side effects of Febstat 40mg Tablet may include:
- Nausea
- Rash
- Headache
- Liver function abnormalities
- Increased serum creatinine levels
- Diarrhea
- Arthralgia (joint pain)
Serious side effects such as severe skin reactions, liver toxicity, or cardiovascular events should be reported to a healthcare provider promptly.
Precautions:
- Use caution in patients with a history of liver or kidney disease, as dosage adjustments may be necessary to prevent potential adverse effects.
- Inform healthcare providers about any history of hypersensitivity reactions to Febuxostat or other medications, as allergic reactions may occur.
- Monitor liver function tests and renal function periodically during treatment with Febstat 40mg Tablet, especially in patients with preexisting hepatic or renal impairment.
- Avoid abrupt discontinuation of Febuxostat therapy, as this may exacerbate gout flares.
When Not to Use:
Febstat 40mg Tablet should not be used in patients with a known hypersensitivity to Febuxostat or any of its components. It is contraindicated in patients with severe liver disease or a history of severe skin reactions (e.g., Stevens-Johnson syndrome or toxic epidermal necrolysis) associated with Febuxostat use.
FAQs (Frequently Asked Questions):
- How long does it take for Febstat 40mg Tablet to lower uric acid levels? The onset of action of Febuxostat may vary, but significant reductions in serum urate levels are typically observed within two weeks of starting treatment.
- Can Febstat 40mg Tablet be taken with food? Febuxostat can be taken with or without food. However, it should be taken consistently, preferably at the same time each day, to maintain steady drug levels in the bloodstream.
- Is Febstat 40mg Tablet safe during pregnancy and breastfeeding? The safety of Febuxostat use during pregnancy and breastfeeding has not been established. Pregnant or breastfeeding women should consult their healthcare provider before using this medication.
- Can Febuxostat cause gout flares? In some cases, initiation of Febuxostat therapy may lead to gout flares initially. This is thought to be due to mobilization of urate crystals from tissues into the bloodstream. Gout flares may be managed with concomitant use of anti-inflammatory medications.
- Are there any drug interactions with Febstat 40mg Tablet? Febuxostat may interact with certain medications, including azathioprine, mercaptopurine, and theophylline. Inform healthcare providers about all medications being taken to avoid potential drug interactions.
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