Onseget 8mg/4ml Injection contains Ondansetron as its active ingredient. Ondansetron belongs to a class of medications called serotonin 5-HT3 receptor antagonists. It is primarily used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery.
Indications:
Onseget 8mg/4ml Injection is indicated for the prevention of nausea and vomiting associated with:
- Chemotherapy-induced nausea and vomiting (CINV)
- Radiation therapy-induced nausea and vomiting (RINV)
- Postoperative nausea and vomiting (PONV)
Dosage and Administration:
- The recommended dosage of Onseget 8mg/4ml Injection varies depending on the specific indication and patient factors.
- It is administered as a slow intravenous (IV) injection or infusion over a prescribed duration.
- The dosage may be adjusted based on the patient’s response and the severity of symptoms.
Precautions:
- Onseget 8mg/4ml Injection should be used with caution in patients with a history of hypersensitivity reactions to ondansetron or other serotonin 5-HT3 receptor antagonists.
- Patients with underlying cardiac conditions, including QT interval prolongation, should be monitored closely during treatment.
- Use with caution in patients with hepatic impairment, as ondansetron metabolism may be altered.
Contraindications:
- Onseget 8mg/4ml Injection is contraindicated in patients with known hypersensitivity to ondansetron or any components of the formulation.
Side Effects:
Common side effects of Onseget 8mg/4ml Injection may include:
- Headache
- Fatigue
- Constipation
- Diarrhea
- Dizziness
- Flushing
- Injection site reactions
- Transient elevation of liver enzymes
Storage:
- Store Onseget 8mg/4ml Injection at room temperature (20-25°C) away from light and moisture.
- Do not freeze the injection.
- Keep the medication out of reach of children.
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