Amantadine began as an antiviral and was later found to help movement symptoms in Parkinson disease by increasing dopamine activity. Today its main use is in Parkinson care, particularly for the involuntary movements caused by long term levodopa.

What Amantadine Is Used For

Parkinson disease, especially stiffness and involuntary movements
Drug induced parkinsonism
Fatigue in multiple sclerosis, on specialist advice
Some influenza A infections, though resistance is now widespread

Common Side Effects

Trouble sleeping and vivid dreams
Dizziness and dry mouth
Ankle swelling
A blotchy purple mottling of the skin on the legs

Precautions

Do not stop it suddenly, as symptoms can worsen sharply. Take the last dose earlier in the day if sleep is disturbed. Report confusion, hallucinations or new leg swelling. Doses are reduced in kidney disease, and older adults are more sensitive to its effects on the mind.

This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.