Cyclodextrins are ring shaped sugar molecules with a pocket in the middle. A poorly soluble medicine can be held inside that pocket, which helps it dissolve and be absorbed faster, so it is used as a carrier rather than as a medicine itself.

Where Cyclodextrin Is Used

  • Piroxicam and other anti inflammatories, for faster absorption
  • Improving the solubility of poorly soluble medicines
  • Masking bitter taste in oral preparations
  • Stabilising ingredients in eye drops and nasal sprays

Common Side Effects

  • Generally none from the carrier itself
  • Loose motions with large amounts by mouth
  • Any side effects usually come from the active medicine

Precautions

Because cyclodextrin is a carrier, the precautions that matter are those of the medicine it carries. A piroxicam beta cyclodextrin tablet, for example, is still an anti inflammatory and carries the usual stomach, kidney and heart cautions. Read the active ingredient on the pack rather than assuming the carrier makes it milder.

This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.