Everolimus
Everolimus blocks a cell signalling pathway called mTOR, which both slows the growth of certain tumours and dampens the immune response. That gives it two roles, in cancer treatment and in preventing transplant rejection, at different doses.
What Everolimus Is Used For
- Certain kidney, breast and neuroendocrine cancers
- Preventing rejection after kidney, liver or heart transplant
- Growths and seizures associated with tuberous sclerosis
Common Side Effects
- Mouth ulcers and sore mouth
- Rash and tiredness
- Raised blood sugar and cholesterol
- Increased risk of infection
Precautions
Blood levels, sugar, cholesterol and blood counts are monitored throughout. Report fever, cough or new breathlessness promptly, since infection and lung inflammation are important risks. Avoid grapefruit and live vaccines. Mouth care from day one reduces ulcers considerably. Take it the same way each day with regard to food, and never adjust the dose yourself.
This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.
