Sulfadoxine is a sulfonamide combined with pyrimethamine. Together they block the malaria parasite's use of folic acid, which stops it from multiplying.

What Sulfadoxine Is Used For

  • Treatment of uncomplicated falciparum malaria, in combination therapy
  • Intermittent preventive treatment of malaria in pregnancy, where recommended
  • Some cases of toxoplasmosis, as advised by a specialist

Common Side Effects

  • Nausea and loss of appetite
  • Headache
  • Skin rash
  • Mouth sores

Precautions

Do not use it if you are allergic to sulfa medicines. Stop immediately and seek urgent help if you develop a rash, blisters, peeling skin or mouth ulcers, as serious skin reactions can occur. Tell your doctor about liver, kidney or blood problems.

This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.

Medicines Containing Sulfadoxine