Agoviz 25mg Tablet

Agoviz 25mg Tablet contains the active ingredient Agomelatine, which is a medication used primarily for the treatment of major depressive disorder (MDD). It belongs to a class of drugs known as melatonergic agonists and selective serotonin (5-HT) antagonists.

Active Ingredient:

Agomelatine (25mg): Agomelatine works by acting as an agonist at melatonin receptors (MT1 and MT2) and as an antagonist at serotonin (5-HT2C) receptors. This dual mechanism of action is thought to regulate circadian rhythms and improve mood in individuals with depression.

Uses:

Agoviz 25mg Tablet is prescribed for the treatment of:

• Major depressive disorder (MDD): It is indicated for adults suffering from depressive episodes associated with MDD.

How it Works:

Agomelatine, the active ingredient in Agoviz 25mg Tablet, acts on two key receptors in the brain:

• Melatonin receptors (MT1 and MT2): Agomelatine acts as an agonist at these receptors, which helps regulate sleep-wake cycles and normalize circadian rhythms.
• Serotonin (5-HT2C) receptors: Agomelatine acts as an antagonist at these receptors, which may enhance the release of other neurotransmitters involved in mood regulation.

Dosage and Administration:

• The dosage of Agoviz 25mg Tablet should be determined by a healthcare provider based on individual patient factors, including the severity of depression and response to treatment.
• It is usually taken orally, once daily at bedtime, with or without food.
• Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet before swallowing.

Side Effects:

Common side effects of Agoviz 25mg Tablet may include:

• Nausea
• Dizziness
• Headache
• Fatigue
• Insomnia or drowsiness
• Abdominal pain
• Constipation
• Increased liver enzymes

Serious side effects such as allergic reactions, hepatotoxicity, or worsening depression may occur rarely but require immediate medical attention.

Precautions:

• Before taking Agoviz 25mg Tablet, inform the healthcare provider about any pre-existing medical conditions, allergies, or medications being taken.
• Use caution in patients with liver impairment, as Agomelatine metabolism may be affected, leading to potential dose adjustments or monitoring.
• It is essential to avoid alcohol consumption while taking Agoviz 25mg Tablet, as it may exacerbate central nervous system depression and increase the risk of side effects.

FAQs:

1. How long does it take for Agoviz 25mg Tablet to work? The onset of action of Agoviz 25mg Tablet varies among individuals, but improvement in depressive symptoms may be observed within a few weeks of starting treatment. It is essential to continue taking the medication as prescribed, even if symptoms improve, to achieve maximum benefit.
2. Can Agoviz 25mg Tablet be taken with other antidepressants? Agoviz 25mg Tablet should generally not be combined with other antidepressants, including selective serotonin reuptake inhibitors (SSRIs) or monoamine oxidase inhibitors (MAOIs), without consulting a healthcare provider. Combining antidepressants may increase the risk of serotonin syndrome or other adverse effects.
3. Is Agoviz 25mg Tablet suitable for elderly patients? Agoviz 25mg Tablet can be used in elderly patients with depression, but dosage adjustments may be necessary based on individual patient factors such as liver function and tolerance to the medication. Regular monitoring is recommended to assess treatment response and potential adverse effects.
4. Can Agoviz 25mg Tablet cause withdrawal symptoms? Abrupt discontinuation of Agoviz 25mg Tablet may lead to withdrawal symptoms such as rebound depression, anxiety, or insomnia. It is essential to gradually taper the dose under the supervision of a healthcare provider when discontinuing treatment to minimize the risk of withdrawal effects.
5. Is Agoviz 25mg Tablet safe during pregnancy or breastfeeding? Agoviz 25mg Tablet is not recommended for use during pregnancy or breastfeeding due to limited safety data. Pregnant or breastfeeding women should consult a healthcare provider for alternative treatment options and appropriate management of depression during pregnancy or lactation.