Co-Diovan 80/12.5mg Tablet

Co-Diovan 80/12.5mg Tablet is a combination medication comprising two active ingredients: valsartan & hydrochlorothiazide. Valsartan belongs to the class of drugs known as angiotensin II receptor blockers (ARBs), while hydrochlorothiazide is a thiazide diuretic. This combination medication is prescribed to treat hypertension (high blood pressure) by lowering blood pressure through complementary mechanisms of action.

Active Ingredients:

• Valsartan: Valsartan works by blocking the action of angiotensin II, a substance that narrows blood vessels, thereby relaxing blood vessels and reducing blood pressure.
• Hydrochlorothiazide: Hydrochlorothiazide increases the excretion of sodium and water by the kidneys, leading to decreased blood volume and reduced vascular resistance, which helps lower blood pressure.

Mechanism of Action:

• Valsartan: Valsartan selectively blocks the binding of angiotensin II to the angiotensin II type 1 (AT1) receptors, resulting in vasodilation and reduced secretion of aldosterone, leading to lowered blood pressure.
• Hydrochlorothiazide: Hydrochlorothiazide inhibits sodium reabsorption in the distal convoluted tubules of the kidneys, promoting diuresis and reducing blood volume and pressure.

Uses:

Co-Diovan 80/12.5mg tablet is indicated for the treatment of hypertension (high blood pressure) in adults when blood pressure is not adequately controlled with monotherapy.

Dosage and Administration:

The recommended dosage of Co-Diovan 80/12.5mg tablet may vary depending on the individual patient’s condition and response to treatment. It is usually taken orally once daily, with or without food. The tablet should be swallowed whole with a glass of water and should not be chewed or crushed.

Side Effects:

Common side effects of Co-Diovan 80/12.5mg tablet may include:

• Dizziness
• Headache
• Fatigue
• Hypotension (low blood pressure)
• Hyperkalemia (high potassium levels)
• Electrolyte imbalances
• Increased uric acid levels
• Impaired kidney function
• Photosensitivity
• Hypersensitivity reactions
• Gastrointestinal disturbances

Precautions:

• Co-Diovan should be used with caution in patients with renal impairment, hepatic impairment, or electrolyte abnormalities.
• It is not recommended for use during pregnancy, especially during the second and third trimesters, as it may cause fetal harm.
• Co-Diovan may interact with other medications, so patients should inform their healthcare provider about all the drugs they are taking.
• Patients should avoid excessive exposure to sunlight or artificial UV rays while taking Co-Diovan, as it may increase the risk of photosensitivity reactions.

Conclusion:

Co-Diovan 80/12.5mg tablet is a combination medication containing valsartan and hydrochlorothiazide, used for the treatment of hypertension in adults. It works by blocking the action of angiotensin II and promoting diuresis, leading to decreased blood pressure. It is important to follow the prescribed dosage and precautions while taking this medication.