Dapxi Met 5/1000mg Tablet

Dapxi Met 5/1000mg Tablet is a combination medication containing two active ingredients: dapagliflozin and metformin hydrochloride. It is used to manage type 2 diabetes mellitus by improving blood sugar control.

Active Ingredients:

• Dapagliflozin: Dapagliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by inhibiting the SGLT2 protein in the kidneys, which reduces glucose reabsorption and increases urinary glucose excretion, thereby lowering blood sugar levels.
• Metformin Hydrochloride: Metformin is a biguanide antidiabetic agent that works by decreasing glucose production in the liver, reducing intestinal glucose absorption, and improving insulin sensitivity in the body’s tissues.

Uses:

Dapxi Met 5/1000mg Tablet is prescribed to treat type 2 diabetes mellitus when diet and exercise alone are not sufficient to control blood sugar levels. It helps lower blood glucose levels by different mechanisms of action, thereby improving glycemic control.

Mechanism of Action:

• Dapagliflozin inhibits the SGLT2 protein in the kidneys, which reduces glucose reabsorption in the renal tubules. This increases urinary glucose excretion and lowers blood glucose levels.
• Metformin decreases hepatic glucose production by inhibiting gluconeogenesis and reduces intestinal glucose absorption. It also enhances insulin sensitivity in peripheral tissues, such as muscle and adipose tissue.

Administration:

Dapxi Met 5/1000mg Tablet is usually taken orally, with or without food, as directed by a healthcare professional. The dosage may vary depending on individual patient factors and response to treatment. It is essential to follow the prescribed dosage and instructions provided by the healthcare provider.

Side Effects:

Common side effects associated with Dapxi Met 5/1000mg Tablet may include:

• Hypoglycemia (low blood sugar)
• Genital yeast infections
• Urinary tract infections
• Increased urination
• Thirst
• Nausea
• Diarrhea
• Abdominal discomfort

Precautions:

Before using Dapxi Met 5/1000mg Tablet, patients should consider the following precautions:

• Inform healthcare providers of any known allergies to dapagliflozin, metformin, or other medications.
• Monitor blood sugar levels regularly, especially during the initial stages of treatment.
• Use caution in patients with renal impairment, as both dapagliflozin and metformin are excreted renally.
• Avoid excessive alcohol consumption, as it may increase the risk of lactic acidosis when using metformin.
• Inform healthcare providers of any other medications, supplements, or herbal products being taken, as they may interact with dapagliflozin or metformin.