Dapxi Met 5/850mg Tablet

Dapxi Met 5/850mg Tablet is a combination medication that contains two active ingredients: dapagliflozin & metformin hydrochloride. It is used to treat type 2 diabetes mellitus in adults. Dapagliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors, while metformin belongs to the biguanide class of antidiabetic drugs. This combination medication helps control blood sugar levels by different mechanisms of action.

Active Ingredients:

• Dapagliflozin: Dapagliflozin works by inhibiting the SGLT2 protein in the kidneys, which reduces the reabsorption of glucose and increases the excretion of glucose in the urine. This leads to a decrease in blood glucose levels.
• Metformin Hydrochloride: Metformin works by decreasing glucose production in the liver and improving insulin sensitivity in muscle cells, thereby reducing blood glucose levels.

Uses:

Dapxi Met 5/850mg Tablet is prescribed for the management of type 2 diabetes mellitus in adults. It helps lower blood sugar levels and may also contribute to weight loss and reduction in blood pressure.

Mechanism of Action:

• Dapagliflozin: Dapagliflozin inhibits the SGLT2 protein in the kidneys, thereby reducing glucose reabsorption from the urine back into the bloodstream. This results in increased urinary glucose excretion and lower blood glucose levels.
• Metformin Hydrochloride: Metformin decreases hepatic glucose production by inhibiting gluconeogenesis and glycogenolysis. It also improves insulin sensitivity in peripheral tissues, such as muscle cells, leading to increased glucose uptake and utilization.

Administration:

Dapxi Met 5/850mg Tablet is usually taken orally, with or without food, as directed by a healthcare professional. The dosage may vary depending on the individual’s condition, response to treatment, and other factors. It is important to follow the prescribed dosage and instructions provided by the healthcare provider.

Side Effects:

Common side effects associated with Dapxi Met 5/850mg Tablet may include:

• Nausea
• Diarrhea
• Urinary tract infections
• Hypoglycemia (low blood sugar)
• Genital yeast infections
• Increased urination
• Headache
• Dizziness

Precautions:

Before using Dapxi Met 5/850mg Tablet, patients should consider the following precautions:

• Inform healthcare providers of any known allergies to dapagliflozin, metformin, or other medications.
• Use caution in patients with kidney problems, as dapagliflozin may increase the risk of dehydration and kidney injury.
• Monitor blood sugar levels regularly during treatment to assess the effectiveness and safety of the medication.
• Avoid alcohol consumption while taking Dapxi Met 5/850mg Tablet, as it may increase the risk of lactic acidosis when combined with metformin.
• Inform healthcare providers of any other medications, supplements, or herbal products being taken, as they may interact with dapagliflozin or metformin.