Glytec M 50/1000mg Tablet

Glytec M 50/1000mg Tablet is a combination medication containing two active ingredients: sitagliptin & metformin. Sitagliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors, while metformin is a biguanide antidiabetic agent. This combination is prescribed for the management of type 2 diabetes mellitus, aiding in controlling blood sugar levels.

Active Ingredients:

• Sitagliptin: It works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which leads to increased levels of incretin hormones. These hormones stimulate insulin secretion and inhibit glucagon release, helping regulate blood sugar levels.
• Metformin: This medication primarily reduces glucose production in the liver and enhances insulin sensitivity in peripheral tissues such as muscle and fat cells. It also improves glucose utilization by these tissues.

Uses

Glytec M Tablet is indicated for the treatment of type 2 diabetes mellitus in adults. It helps control blood sugar levels by:

• Stimulating insulin secretion
• Decreasing glucose production in the liver
• Increasing peripheral glucose uptake

Mechanism of Action:

The combination of sitagliptin and metformin works synergistically to improve glycemic control in patients with type 2 diabetes mellitus. Sitagliptin increases incretin hormone levels, leading to enhanced insulin secretion and reduced glucagon release. Metformin decreases hepatic glucose production and enhances peripheral glucose utilization, thereby improving blood sugar levels.

Administration:

Glytec M Tablet is typically taken orally with meals to reduce gastrointestinal side effects. Dosage and administration frequency may vary depending on the patient’s condition and response to treatment. Patients should follow the dosage instructions provided by their healthcare provider.

Side Effects:

Common side effects associated with Glytec M Tablet may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Headache
• Hypoglycemia (low blood sugar), particularly when used in combination with other antidiabetic medications

Precautions:

Before taking Glytec M Tablet, patients should consider the following precautions:

• Inform healthcare providers of any known allergies to sitagliptin, metformin, or other medications.
• Monitor blood sugar levels regularly, especially during the initial stages of treatment or when adjustments are made to the dosage.
• Exercise caution in patients with renal impairment, as metformin may accumulate and increase the risk of lactic acidosis.
• Avoid excessive alcohol consumption while using Glytec M Tablet, as it may increase the risk of lactic acidosis.