Glytec M 50/500mg Tablet

Glytec M 50/500mg Tablet is a combination medication comprising two active ingredients: Sitagliptin & Metformin. Sitagliptin is categorized as a dipeptidyl peptidase-4 (DPP-4) inhibitor, while metformin is classified as a biguanide antidiabetic agent. This combination is prescribed for the management of type 2 diabetes mellitus, aiding in the regulation of blood sugar levels.

Active Ingredients:

• Sitagliptin: Acts by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), leading to increased levels of incretin hormones. These hormones stimulate insulin secretion and inhibit glucagon release, thereby assisting in the regulation of blood sugar levels.
• Metformin: Primarily reduces glucose production in the liver and enhances insulin sensitivity in peripheral tissues such as muscle and fat cells. It also improves glucose utilization by these tissues.

Uses:

Glytec M Tablet is indicated for the treatment of type 2 diabetes mellitus in adults. It helps control blood sugar levels by:

• Stimulating insulin secretion
• Decreasing hepatic glucose production
• Increasing peripheral glucose uptake

Mechanism of Action:

The combination of sitagliptin and metformin synergistically improves glycemic control in patients with type 2 diabetes mellitus. Sitagliptin increases incretin hormone levels, resulting in enhanced insulin secretion and reduced glucagon release. Metformin decreases hepatic glucose production and enhances peripheral glucose utilization, thereby improving blood sugar levels.

Administration:

Glytec M Tablet is usually taken orally with meals to minimize gastrointestinal side effects. Dosage and frequency of administration may vary depending on the patient’s condition and response to treatment. Patients should adhere to the dosage instructions provided by their healthcare provider.

Side Effects:

Common side effects associated with Glytec M Tablet may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Headache
• Hypoglycemia (low blood sugar), particularly when used concomitantly with other antidiabetic medications

Precautions:

Before taking Glytec M Tablet, patients should consider the following precautions:

• Inform healthcare providers about any known allergies to sitagliptin, metformin, or other medications.
• Monitor blood sugar levels regularly, especially during the initial stages of treatment or when adjustments are made to the dosage.
• Exercise caution in patients with renal impairment, as metformin may accumulate and increase the risk of lactic acidosis.
• Avoid excessive alcohol consumption while using Glytec M Tablet, as it may elevate the risk of lactic acidosis.