Neuletroz 2.5mg Tablet

Neuletroz 2.5mg Tablet contains the active ingredient letrozole, which is classified as a nonsteroidal aromatase inhibitor. It is primarily prescribed for the treatment of hormone receptor-positive breast cancer in postmenopausal women.

Active Ingredient:

• Letrozole: Letrozole works by inhibiting the aromatase enzyme, which is responsible for the conversion of androgens to estrogens in peripheral tissues. By blocking estrogen production, letrozole helps reduce estrogen levels in the body, which can slow down or stop the growth of hormone-sensitive breast cancer cells.

Uses:

Neuletroz 2.5mg Tablet is used for the following purposes:

1. Breast Cancer: It is indicated for the adjuvant treatment of hormone receptor-positive early breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy.
2. Advanced Breast Cancer: Letrozole may be prescribed for the treatment of advanced or metastatic breast cancer in postmenopausal women who have experienced disease progression following antiestrogen therapy.

Mechanism of Action:

Letrozole exerts its pharmacological effects by selectively inhibiting the aromatase enzyme, which is responsible for the conversion of androgens (such as testosterone) to estrogens (such as estradiol). By blocking estrogen production, letrozole reduces estrogen levels in the body, which can inhibit the growth of hormone-sensitive breast cancer cells.

Administration:

Neuletroz 2.5mg Tablet is usually taken orally, once daily, with or without food, as directed by a healthcare professional. The duration of treatment and dosage may vary depending on the individual patient’s condition and response to therapy. It is important to take the medication regularly and at the same time each day.

Side Effects:

Common side effects associated with letrozole may include:

• Hot flashes
• Fatigue
• Sweating
• Joint pain or stiffness
• Headache
• Nausea
• Vaginal dryness or irritation
• Bone thinning (osteoporosis)

Precautions:

• Letrozole should be used with caution in patients with a history of osteoporosis or bone fractures, as it may further increase the risk of bone thinning.
• It is not recommended for use in premenopausal women or individuals with preexisting liver disease.
• Letrozole may cause fetal harm and is contraindicated during pregnancy. It should not be used in women of reproductive potential unless necessary.

Contraindications:

• Neuletroz 2.5mg Tablet is contraindicated in women who are pregnant, breastfeeding, or planning to become pregnant.
• It should not be used in individuals with a known hypersensitivity to letrozole or any of the inactive ingredients in the formulation.