Trikat MR 35mg Tablet

Trikat MR 35mg Tablet contains the active ingredient Trimetazidine Dihydrochloride. It belongs to the class of medications known as metabolic agents. Trimetazidine is primarily used in the treatment of angina pectoris and other cardiovascular conditions.

Uses:

• Trikat MR 35mg Tablet is indicated for the treatment of stable angina pectoris, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart muscle.
• It is used as an adjunctive therapy in patients with stable angina who are inadequately controlled with other antianginal medications such as beta-blockers and nitrates.
• Trimetazidine may also be prescribed for other cardiovascular conditions such as heart failure and ischemic heart disease.

How It Works:

• Trimetazidine exerts its therapeutic effects by modulating cellular energy metabolism. It improves myocardial glucose utilization and shifts myocardial energy production from fatty acid oxidation to glucose oxidation.
• By optimizing myocardial energy metabolism, Trimetazidine helps preserve myocardial function, reduce ischemia-related symptoms, and improve exercise tolerance in patients with angina pectoris.

Dosage:

• The dosage of Trikat MR 35mg Tablet should be determined by a healthcare professional based on the severity of the angina symptoms, patient’s medical history, and other factors.
• It is typically taken orally with a full glass of water, preferably with meals to enhance absorption and reduce gastrointestinal side effects.
• The tablet should be swallowed whole and should not be chewed, crushed, or broken.

Precautions:

• Use Trikat MR 35mg Tablet with caution in patients with severe renal impairment or hepatic dysfunction.
• It should be used with caution in elderly patients and those with a history of Parkinson’s disease, as Trimetazidine may exacerbate Parkinsonian symptoms.
• Monitor patients receiving Trimetazidine for signs of adverse effects such as dizziness, headache, gastrointestinal disturbances, or worsening angina symptoms.

Side Effects:

Common side effects of Trikat MR 35mg Tablet may include dizziness, headache, nausea, vomiting, and gastrointestinal disturbances. Rare but serious side effects such as allergic reactions, hypotension, and bradycardia may occur.

When Not to Use:

• Trikat MR 35mg Tablet is contraindicated in patients with hypersensitivity to Trimetazidine or any of the components of the formulation.
• It should not be used in patients with acute coronary syndrome, severe hypotension, or cardiogenic shock.
• Avoid concomitant use of Trimetazidine with other drugs known to prolong the QT interval or induce torsades de pointes.

FAQ:

1. How long does it take for Trikat MR 35mg Tablet to work? The onset of action of Trimetazidine varies depending on the individual’s response and the severity of the angina symptoms. Improvement in symptoms may be observed within days to weeks of starting treatment.
2. Can Trikat MR 35mg Tablet be used during pregnancy or breastfeeding? The safety of Trimetazidine during pregnancy and breastfeeding has not been established. It should only be used if the potential benefits outweigh the risks to the mother and fetus or infant.
3. Is Trikat MR 35mg Tablet addictive? Trimetazidine is not considered addictive when used as directed by a healthcare professional. However, it should be used with caution in patients with a history of substance abuse or addiction.