Zepres Plus 10/25mg Tablet

Zepres Plus 10/25mg Tablet is a combination medication that contains two active ingredients: Enalapril Maleate & Hydrochlorothiazide. Enalapril Maleate belongs to the class of medications known as angiotensin-converting enzyme (ACE) inhibitors, while Hydrochlorothiazide is a thiazide diuretic. This combination is used to treat hypertension (high blood pressure) by lowering blood pressure and reducing fluid retention in the body.

Uses:

• Zepres Plus 10/25mg Tablet is indicated for the treatment of hypertension (high blood pressure).
• It is particularly useful in patients who require dual therapy for optimal blood pressure control.
• Enalapril Maleate works by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, thereby relaxing blood vessels and lowering blood pressure.
• Hydrochlorothiazide acts as a diuretic, promoting the excretion of sodium and water from the body, which helps reduce fluid volume and blood pressure.

How It Works:

• Enalapril Maleate inhibits the action of angiotensin-converting enzyme (ACE), which catalyzes the conversion of angiotensin I to angiotensin II. By blocking this enzyme, enalapril reduces the production of angiotensin II, a potent vasoconstrictor, leading to vasodilation and decreased blood pressure.
• Hydrochlorothiazide works by increasing the excretion of sodium and water in the urine, which reduces fluid volume and blood pressure.

Dosage:

• The dosage of Zepres Plus 10/25mg Tablet should be determined by a healthcare professional based on the individual’s blood pressure response and medical history.
• It is typically taken orally once daily, with or without food.

Precautions:

• Use Zepres Plus 10/25mg Tablet with caution in patients with a history of angioedema or hypersensitivity reactions to ACE inhibitors.
• Monitor blood pressure regularly and adjust the dosage of Zepres Plus as needed to achieve optimal blood pressure control.
• Inform your healthcare provider about any medications, supplements, or herbal products you are taking, as they may interact with Zepres Plus.

Side Effects:

Common side effects of Zepres Plus 10/25mg Tablet may include dizziness, headache, fatigue, hypotension (low blood pressure), dry cough (associated with ACE inhibitors), electrolyte imbalances, and increased urination.

When Not to Use:

• Zepres Plus 10/25mg Tablet is contraindicated in patients with a history of hypersensitivity reactions to ACE inhibitors or thiazide diuretics, or those with a history of angioedema associated with previous ACE inhibitor therapy.
• It should not be used during pregnancy, especially during the second and third trimesters, due to the risk of fetal harm.

FAQ:

1. Can Zepres Plus 10/25mg Tablet be taken with food? Zepres Plus 10/25mg Tablet can be taken with or without food. However, it is important to take it consistently at the same time each day.
2. How long does it take for Zepres Plus 10/25mg Tablet to lower blood pressure? The onset of action of Zepres Plus 10/25mg Tablet varies from person to person. Blood pressure-lowering effects may be observed within a few hours to several weeks of starting treatment.
3. Is Zepres Plus 10/25mg Tablet safe for use in elderly patients? Zepres Plus 10/25mg Tablet can be used in elderly patients, but dosage adjustments may be necessary due to age-related changes in renal function and blood pressure sensitivity.