About this product
Overview
Maxpime 1g Injection contains the active ingredient cefepime, which is a fourth-generation cephalosporin antibiotic. It is formulated for intravenous administration and is used to treat a wide range of bacterial infections. Cefepime is known for its broad spectrum of activity against both Gram-positive and Gram-negative bacteria, including many multi-drug resistant strains.
Uses
- Bacterial Infections: Maxpime Injection is indicated for the treatment of various bacterial infections, including:
- Respiratory tract infections such as pneumonia and bronchitis.
- Urinary tract infections including cystitis and pyelonephritis.
- Skin and soft tissue infections such as cellulitis and wound infections.
- Intra-abdominal infections such as peritonitis and cholecystitis.
- Septicemia and bacteremia.
- Febrile neutropenia in immunocompromised patients.
Mechanism of Action
Cefepime exerts its antibacterial effects by inhibiting bacterial cell wall synthesis. It achieves this by binding to penicillin-binding proteins (PBPs) located on the bacterial cell membrane, thereby interfering with cell wall formation. This leads to cell wall instability and ultimately bacterial cell death.
Dosage and Administration
- The dosage of Maxpime Injection and the duration of treatment depend on the type and severity of the infection, as well as the patient’s age, weight, and renal function.
- It is administered via intravenous infusion over a period determined by the healthcare provider, typically in a healthcare setting such as a hospital or clinic.
Side Effects
While generally well-tolerated, Maxpime Injection may cause some side effects, including:
- Gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain.
- Allergic reactions ranging from rash and itching to severe hypersensitivity reactions such as anaphylaxis.
- Injection site reactions such as pain, swelling, or redness.
- Headache, dizziness, and fatigue.
- Changes in liver function tests.
- Pseudomembranous colitis (rare but serious).
Precautions
- Inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking before receiving Maxpime Injection.
- Use with caution in patients with a history of allergic reactions to cephalosporins or penicillins.
- Close monitoring of renal function, liver function, and complete blood count (CBC) is recommended during prolonged therapy.
- Avoid using Maxpime Injection in patients with known hypersensitivity to cefepime or any components of the injection.
When Not to Use
Maxpime Injection should be avoided in patients with:
- Known hypersensitivity to cefepime or any components of the injection.
- History of severe allergic reactions to cephalosporins or penicillins.
- Neonates with hyperbilirubinemia, particularly those receiving phototherapy, as cefepime may displace bilirubin from albumin and lead to kernicterus.
Substitutes for Maxpime 1g Injection
These medicines contain the same salt as Maxpime 1g Injection (Cefepime 1g), so they are common substitutes. Compare their prices, and change brands only after checking with your doctor or pharmacist.
| Medicine | Manufacturer | Pack | Price |
|---|---|---|---|
| Fectopime 1g Injection | Getz Pharma | 1 | Rs 740 |
| Fectopime 1g Inejction | Getz Pharma | 1,S | Rs 809.52 |
Other strengths of Cefepime
| Medicine | Manufacturer | Strength | Price |
|---|---|---|---|
| GU-Pime 500mg injection | Glit Pharma | 500mg | Rs 564 |
| Maxpime 500mg Injection | Glaxo Smithkline | 500mg | Rs 573.49 |
| Fectopime 500mg Injection | Getz Pharma | 500mg | Rs 574.32 |
| Zepim 500mg injection | Global-Vision | 500mg | Rs 600 |
See all brands and prices on our Cefepime page.
Frequently asked questions
How often should Maxpime Injection be administered?
The frequency of administration and duration of treatment with Maxpime Injection depend on the type and severity of the infection. Follow your healthcare provider’s instructions.
Can Maxpime Injection be used during pregnancy?
Maxpime Injection should only be used during pregnancy if the potential benefits outweigh the risks. Consult your doctor for personalized advice.
Is it safe to consume alcohol while receiving Maxpime Injection?
It is generally advisable to avoid alcohol while undergoing antibiotic treatment as it may interfere with the effectiveness of the medication and increase the risk of side effects.
What should I do if I miss a dose of Maxpime Injection?
If you miss a dose, contact your healthcare provider for instructions. Do not double the dose to make up for a missed one.
Can Maxpime Injection be used in pediatric patients?
Maxpime Injection may be used in pediatric patients under the guidance of a healthcare provider, adjusting the dosage based on the child’s weight and condition.
This information is for general awareness only. It does not replace advice from your doctor or pharmacist. Always read the leaflet and follow the directions you were given.
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