Isophane insulin is insulin combined with protamine so that it is absorbed slowly from the injection site. That slower release gives background cover lasting most of the day, which is why it is described as intermediate acting.

What Isophane Insulin Is Used For

Background insulin cover in diabetes
Combination with short acting insulin at mealtimes
Type 2 diabetes when oral medicines are no longer sufficient

Common Side Effects

Low blood sugar, most often overnight
Weight gain
Changes in the fat under the skin at injection sites
Local reactions

Precautions

It is a cloudy suspension and must be gently rolled until evenly mixed before each dose. Rotate injection sites so the skin does not thicken, as thickened areas absorb insulin unpredictably. Keep glucose with you, and make sure someone at home knows how to recognise and treat a hypo. Dose changes belong with your doctor.

This page is general information only. It is not a substitute for advice from your doctor or pharmacist, and it does not include dosage. Always follow the directions given to you and read the leaflet inside the pack.