Gvia M 50/500mg Tablet

Gvia M 50/500mg Tablet is a combination medication containing two active ingredients: sitagliptin and metformin. Sitagliptin belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors, while metformin is a biguanide antidiabetic agent. This combination is formulated to help manage type 2 diabetes mellitus by improving glycemic control through different mechanisms of action.

Ingredients:

1. Sitagliptin: Sitagliptin works by inhibiting the enzyme DPP-4, which in turn increases the levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones help regulate blood glucose levels by stimulating insulin release and inhibiting glucagon secretion.
2. Metformin: Metformin primarily works by decreasing hepatic glucose production, enhancing insulin sensitivity in peripheral tissues, and reducing intestinal glucose absorption. It helps lower blood glucose levels by improving insulin action and reducing insulin resistance.

Uses:

Gvia M 50/500mg Tablet is prescribed for the following purposes:

• Management of type 2 diabetes mellitus: Gvia M 50/500mg Tablet is used to improve glycemic control in adults with type 2 diabetes mellitus, either as initial therapy or in combination with other antidiabetic medications such as sulfonylureas, thiazolidinediones, or insulin.
• Reduction of fasting and postprandial blood glucose levels: The combination of sitagliptin and metformin helps lower fasting and postprandial blood glucose levels by targeting different pathways involved in glucose regulation.

Side Effects:

While Gvia M 50/500mg Tablet is generally well-tolerated, some individuals may experience side effects, including:

• Nausea or vomiting
• Diarrhea
• Abdominal discomfort or bloating
• Headache
• Hypoglycemia (low blood sugar) when used with other antidiabetic medications
• Nasopharyngitis (inflammation of the nose and throat)
• Upper respiratory tract infection

Rare but serious side effects may include lactic acidosis (a buildup of lactic acid in the blood), pancreatitis, or allergic reactions. If you experience any severe or persistent side effects, inform your healthcare provider promptly.

Precautions:

• Inform your healthcare provider about any pre-existing medical conditions, allergies, or medications you are currently taking before starting Gvia M 50/500mg Tablet.
• Take Gvia M 50/500mg Tablet as directed by your doctor. Follow the prescribed dosage, frequency, and duration of treatment to achieve optimal glycemic control and minimize the risk of adverse effects.
• Monitor your blood glucose levels regularly as directed by your healthcare provider and report any abnormal readings promptly.

When Not to Use:

Gvia M 50/500mg Tablet should not be used in individuals with:

• Known hypersensitivity or allergy to sitagliptin, metformin, or any components of the tablet
• Severe renal impairment or acute renal failure
• Metabolic acidosis, diabetic ketoacidosis, or lactic acidosis
• History of pancreatitis or severe gastrointestinal disorders

FAQ:

1. How should Gvia M 50/500mg Tablet be taken? Take Gvia M 50/500mg Tablet orally, with meals, as directed by your healthcare provider. Swallow the tablet whole with a glass of water. Do not crush, chew, or split the tablet unless instructed otherwise.
2. Can Gvia M 50/500mg Tablet be used alone or with other antidiabetic medications? Gvia M 50/500mg Tablet can be used alone as monotherapy or in combination with other antidiabetic medications such as sulfonylureas, thiazolidinediones, or insulin, depending on the individual’s glycemic control and treatment goals.
3. Are there any special dietary considerations while taking Gvia M 50/500mg Tablet? Maintain a healthy diet and lifestyle modifications, including regular exercise and weight management, to complement the effects of Gvia M 50/500mg Tablet on glycemic control. Follow a balanced diet as recommended by your healthcare provider or dietitian.
4. Can Gvia M 50/500mg Tablet be used during pregnancy or breastfeeding? The use of Gvia M 50/500mg Tablet during pregnancy or breastfeeding should be discussed with a healthcare provider. The potential risks and benefits of treatment must be carefully weighed before initiating therapy in pregnant or breastfeeding individuals.
5. What should I do if I miss a dose of Gvia M 50/500mg Tablet? If you miss a dose of Gvia M 50/500mg Tablet, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.