Heamaccel Injection 500ml contains Polygeline as its active ingredient. Polygeline, also known as modified fluid gelatin, is a colloid solution used for intravenous administration to expand blood volume and restore circulating blood volume in cases of hypovolemia or shock.
Ingredients:
- Polygeline: Polygeline is a synthetic colloid solution derived from gelatin. It works by increasing the oncotic pressure of the blood plasma, thereby drawing fluid from the interstitial space into the intravascular compartment and expanding blood volume.
Uses:
Heamaccel Injection 500ml is indicated for the treatment of hypovolemia or shock due to various causes, including hemorrhage, trauma, surgery, dehydration, or sepsis. It helps restore blood volume and improve tissue perfusion in critically ill patients.
Side Effects:
- Fluid Overload: Rapid administration of Polygeline may lead to fluid overload, especially in patients with impaired cardiac or renal function.
- Hypersensitivity Reactions: Allergic reactions to Polygeline, although rare, may manifest as rash, itching, swelling, or difficulty breathing.
- Coagulopathy: Prolonged or repeated use of Polygeline may interfere with blood coagulation and platelet function, leading to bleeding or clotting disorders.
- Renal Dysfunction: Polygeline may exacerbate renal dysfunction or acute kidney injury, particularly in patients with pre-existing renal impairment.
Precautions:
- Cardiovascular Status: Use with caution in patients with cardiac insufficiency, hypertension, or pulmonary edema, as fluid administration may exacerbate these conditions.
- Renal Function: Monitor renal function regularly, especially in patients at risk of renal impairment, and adjust the dosage of Polygeline accordingly.
- Hypervolemia: Avoid overhydration and monitor fluid balance closely to prevent hypervolemia and associated complications.
- Hypersensitivity: Patients with a history of allergic reactions to gelatin or other colloid solutions should be monitored closely for signs of hypersensitivity reactions.
When Not to Use:
Heamaccel Injection 500ml should not be used in patients with:
- Known hypersensitivity to Polygeline or any component of the injection.
- Severe cardiac insufficiency, pulmonary edema, or renal failure requiring dialysis.
- Severe coagulopathy or bleeding disorders.
FAQ:
- How is Heamaccel Injection 500ml administered?
- Heamaccel Injection 500ml is administered intravenously over a period of time determined by the healthcare provider, usually at a controlled rate to prevent rapid fluid overload.
- What should I do if I experience an allergic reaction to Heamaccel Injection?
- If you experience signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, discontinue the infusion immediately and seek medical attention.
- Can Heamaccel Injection 500ml be used in pediatric patients?
- Heamaccel Injection 500ml may be used in pediatric patients under the supervision of a healthcare provider, but the dosage and administration should be adjusted based on the child’s age, weight, and clinical condition.
- Is Heamaccel Injection 500ml safe during pregnancy and breastfeeding?
- The safety of Heamaccel Injection 500ml during pregnancy and breastfeeding has not been established. It should be used during pregnancy or breastfeeding only if the potential benefits outweigh the risks to the mother and fetus or infant.
- Can Heamaccel Injection 500ml be used for fluid resuscitation in hemorrhagic shock?
- Heamaccel Injection 500ml may be used for fluid resuscitation in hemorrhagic shock, but other measures such as blood transfusion and surgical intervention may also be necessary depending on the severity and cause of the shock.
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