Sitaphage 50/500mg Tablet

Sitaphage 50/500mg tablet is an oral antidiabetic medication that combines two active ingredients, Sitagliptin and Metformin, both of which play a significant role in managing type 2 diabetes. This combination therapy is designed to improve blood sugar control in adults when treatment with either Sitagliptin or Metformin alone is not sufficient, or as part of a broader diabetes treatment plan that may include diet and exercise.

Uses:

Sitaphage is specifically used for the treatment of type 2 diabetes mellitus in adults. Metformin works by decreasing glucose production in the liver, reducing glucose absorption in the intestines, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization. Sitagliptin, on the other hand, works by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme, which results in increased levels of incretin hormones. These hormones help to regulate glucose homeostasis by increasing insulin synthesis and release from the pancreas, and by decreasing glucagon secretion in a glucose-dependent manner.

Side Effects:

Common side effects of Sitaphage may include gastrointestinal symptoms such as nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Some individuals may experience a metallic taste in the mouth from Metformin. Sitagliptin has been associated with a risk of developing pancreatitis. Although rare, there’s a potential risk of lactic acidosis with Metformin, particularly in patients with renal impairment or conditions that predispose to hypoxia.

Precautions:

Before taking Sitaphage, it is essential to inform your healthcare provider about your medical history, especially kidney or liver disease, heart failure, or if you are prone to dehydration. It’s also crucial to mention any other medications you are taking to avoid potential interactions. Regular monitoring of kidney function is recommended while on Sitaphage.

Patients should be aware of the symptoms of hypoglycemia (low blood sugar) and how to manage them. Also, the risk of lactic acidosis, although rare, necessitates awareness of its symptoms, such as muscle pain, difficulty breathing, stomach pain, dizziness, and feeling cold.

When Not to Use:

Sitaphage is contraindicated in patients with severe renal impairment, metabolic acidosis, including diabetic ketoacidosis, or hypersensitivity to either Sitagliptin or Metformin. It should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.

FAQ:

1. Can Sitaphage be used in type 1 diabetes?
   • No, Sitaphage is designed for the management of type 2 diabetes only.
2. What should I do if I miss a dose of Sitaphage?
   • If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double doses.
3. Can I consume alcohol while taking Sitaphage?
   • Alcohol is not recommended as it can increase the risk of lactic acidosis with Metformin.
4. How should Sitaphage be taken?
   • Sitaphage should be taken as prescribed by your healthcare provider, usually with meals to reduce gastrointestinal side effects.
5. Does Sitaphage cause weight gain?
   • Unlike some other diabetes medications, Sitaphage does not typically cause weight gain and may lead to a modest weight loss in some individuals.