SENSOCAIN SPINAL 0.5% INJECTION

SENSOCAIN SPINAL 0.5% INJECTION contains Bupivacaine Hydrochloride as its active ingredient. It is a sterile solution used for spinal anesthesia, a type of regional anesthesia that numbs a specific part of the body to block pain during surgical procedures or childbirth. Bupivacaine is a long-acting local anesthetic that works by blocking nerve signals in the spinal cord.

Uses:

SENSOCAIN SPINAL 0.5% INJECTION is indicated for spinal anesthesia in surgical procedures requiring anesthesia below the level of the umbilicus, including lower limb surgeries, cesarean sections, and urological procedures. It can also be used for pain relief during labor and delivery.

Mechanism of Action:

Bupivacaine Hydrochloride exerts its pharmacological effects by blocking the transmission of pain signals from nerves in the spinal cord. It does this by inhibiting the influx of sodium ions through voltage-gated sodium channels in nerve cell membranes, preventing the generation and conduction of nerve impulses.

Dosage and Administration:

The dosage of SENSOCAIN SPINAL 0.5% INJECTION is determined by the patient’s weight, age, and the specific surgical procedure. It is administered via lumbar puncture (spinal injection) under sterile conditions by a qualified healthcare professional. The dose may vary depending on the extent and duration of anesthesia required.

Precautions:

1. Hypotension: SENSOCAIN SPINAL 0.5% INJECTION may cause a decrease in blood pressure, especially when administered rapidly or in high doses. Monitoring of blood pressure and cardiovascular function is essential during and after administration.
2. Respiratory Depression: Inadvertent intravascular injection or high doses of bupivacaine can lead to systemic toxicity, resulting in central nervous system depression and respiratory depression. Aspiration prior to injection and cautious dosing techniques are recommended.
3. Neurotoxicity: Prolonged or excessive use of local anesthetics like bupivacaine may lead to neurotoxic effects, including nerve damage or persistent neurologic deficits. The lowest effective dose should be used to minimize the risk.
4. Allergic Reactions: Patients with a known hypersensitivity to amide-type local anesthetics should avoid the use of SENSOCAIN SPINAL 0.5% INJECTION. Allergic reactions, though rare, may occur and require prompt medical attention.

Side Effects:

Common side effects associated with SENSOCAIN SPINAL 0.5% INJECTION may include hypotension, bradycardia, nausea, vomiting, headache, backache, and transient neurological symptoms such as numbness or tingling in the lower extremities. Serious adverse effects such as cardiac arrest, respiratory arrest, and seizures are rare but possible.

In Summary:

SENSOCAIN SPINAL 0.5% INJECTION containing Bupivacaine Hydrochloride is a local anesthetic used for spinal anesthesia during surgical procedures and for pain relief during labor and delivery. It works by blocking nerve signals in the spinal cord to provide anesthesia to the lower body while allowing the patient to remain conscious.