Neodipar 850mg Tablet

Neodipar 850mg Tablet contains the active ingredient Metformin, which belongs to the class of medications known as biguanides. It is primarily prescribed for the management of type 2 diabetes mellitus, a condition characterized by high blood sugar levels due to insulin resistance or insufficient insulin production.

Uses:

1. Type 2 Diabetes Mellitus: Neodipar 850mg Tablet is used to control blood sugar levels in individuals with type 2 diabetes mellitus, either alone or in combination with other antidiabetic medications.
2. Blood Sugar Regulation: It helps to lower fasting and postprandial (after-meal) blood glucose levels by decreasing hepatic glucose production and increasing peripheral glucose uptake and utilization.
3. Glycemic Control: Neodipar 850mg Tablet can help reduce HbA1c levels, a marker of long-term blood glucose control, thereby reducing the risk of diabetes-related complications.
4. Polycystic Ovary Syndrome (PCOS): In some cases, Metformin may be prescribed off-label to manage symptoms of polycystic ovary syndrome, such as irregular menstrual cycles, infertility, and insulin resistance.

Side Effects:

1. Gastrointestinal Upset: Common side effects include nausea, vomiting, diarrhea, abdominal discomfort, and bloating, particularly during the initial stages of treatment. These symptoms often resolve with continued use or dose adjustment.
2. Hypoglycemia: Metformin does not typically cause hypoglycemia (low blood sugar) when used as monotherapy. However, when combined with other antidiabetic medications such as sulfonylureas or insulin, the risk of hypoglycemia may increase.
3. Lactic Acidosis: Although rare, Metformin may increase the risk of lactic acidosis, a potentially life-threatening condition characterized by elevated blood lactate levels. Symptoms include weakness, difficulty breathing, abdominal pain, and confusion. Prompt medical attention is required if lactic acidosis is suspected.
4. Vitamin B12 Deficiency: Long-term use of Metformin may be associated with vitamin B12 deficiency, leading to symptoms such as anemia, neuropathy, or megaloblastic changes in the blood. Regular monitoring of vitamin B12 levels is recommended, and supplementation may be necessary in some cases.

Precautions:

1. Renal Impairment: Neodipar 850mg Tablet should be used with caution in individuals with impaired renal function, as Metformin is excreted primarily by the kidneys. Dosage adjustment may be necessary to prevent drug accumulation and potential toxicity.
2. Hepatic Impairment: Patients with severe hepatic impairment should avoid the use of Metformin due to the increased risk of lactic acidosis.
3. Heart Failure: Metformin should be used cautiously in individuals with congestive heart failure, as it may exacerbate fluid retention and increase the risk of lactic acidosis.
4. Surgery and Imaging Procedures: Metformin should be temporarily discontinued before scheduled surgeries or radiographic procedures involving intravascular administration of iodinated contrast agents to reduce the risk of lactic acidosis.

When Not to Use:

Neodipar 850mg Tablet should not be used in individuals with a known hypersensitivity to Metformin or any other component of the formulation. It is also contraindicated in patients with severe renal impairment (eGFR <30 mL/min/1.73 m²), acute or chronic metabolic acidosis, or a history of lactic acidosis.

FAQ:

1. How should Neodipar 850mg Tablet be taken?
   • Neodipar 850mg Tablet is usually taken orally with meals to reduce gastrointestinal side effects. The dosage is determined by a healthcare professional and may be adjusted based on blood glucose levels and tolerance.
2. Can Neodipar 850mg Tablet be used for type 1 diabetes mellitus?
   • No, Neodipar 850mg Tablet is specifically indicated for the management of type 2 diabetes mellitus and is not effective in individuals with type 1 diabetes, who require insulin therapy.
3. Is Neodipar 850mg Tablet safe during pregnancy and breastfeeding?
   • The safety of Metformin during pregnancy and lactation is still under debate. Pregnant or breastfeeding women should consult a healthcare professional before initiating or continuing treatment with Neodipar 850mg Tablet.
4. Can Neodipar 850mg Tablet cause weight loss?
   • While some individuals may experience mild weight loss as a side effect of Metformin therapy, significant weight loss is not a guaranteed outcome. Weight changes may vary among individuals and depend on factors such as diet, exercise, and overall health status.