Evopride 1/500mg Tablet

Evopride 1/500mg Tablet is a combination oral medication containing two active ingredients, Glimepiride and Metformin, which are used to treat type 2 diabetes mellitus. This medication is designed to help control blood glucose levels in patients who are unable to achieve adequate control with diet and exercise alone. Glimepiride belongs to a class of drugs known as sulfonylureas, which stimulate the release of insulin from the pancreas. Metformin, on the other hand, works by decreasing glucose production in the liver and improving insulin sensitivity, enhancing glucose uptake by tissues.

Uses:

• Management of type 2 diabetes mellitus in adults.
• Improvement of glycemic control when diet, exercise, and the single use of Glimepiride or Metformin have not resulted in adequate glycemic control.
• Reduction of complications associated with high blood sugar levels, such as nerve damage, kidney damage, and cardiovascular disease.

How it Works:

Evopride 1/500mg Tablet works through a dual mechanism:

1. Glimepiride stimulates the pancreatic beta cells to produce more insulin, which helps lower blood sugar levels.
2. Metformin reduces the amount of glucose produced by the liver, decreases the absorption of glucose from the intestines, and enhances the sensitivity of muscle cells to insulin.

This combination results in a more effective reduction in blood glucose levels than either component alone.

Dosage and Administration:

Evopride 1/500mg Tablets are typically taken once or twice daily with meals to reduce the risk of gastrointestinal side effects. The exact dosage and regimen depend on the patient’s current treatment, effectiveness, and tolerance of the medication, and should be determined by a healthcare provider.

Side Effects:

Common side effects of Evopride 1/500mg Tablet may include:

• Hypoglycemia (especially if taken without adequate food)
• Nausea and diarrhea (mostly associated with Metformin)
• Headache
• Dizziness
• Abdominal pain
• Weight gain (possible with Glimepiride)

More serious side effects could include lactic acidosis, a rare but serious condition associated with Metformin. Symptoms of lactic acidosis include muscle pain, breathing difficulties, stomach discomfort, dizziness, and feeling cold.

Precautions:

• Patients with kidney or liver problems should use this medication with caution.
• Regular monitoring of blood glucose levels is recommended to adjust the dose accordingly.
• Avoid excessive alcohol intake, as it can increase the risk of lactic acidosis with Metformin.
• Inform the doctor of any other medications being taken, as there are potential interactions with other drugs.

When Not to Use:

Evopride 1/500mg Tablet should not be used in patients with:

• Known allergies to Glimepiride, Metformin, or other sulfonylureas.
• Diabetic ketoacidosis or diabetic coma.
• Severe renal or hepatic impairment.
• Acute or chronic metabolic acidosis.

FAQs:

1. Can I stop taking Evopride 1/500mg if my blood sugar levels are normal? No, you should continue taking your medication as prescribed by your healthcare provider. Abruptly stopping can lead to uncontrolled blood sugar levels.
2. Can Evopride 1/500mg Tablet cause weight gain? Yes, Glimepiride can cause weight gain. It’s important to maintain a healthy diet and exercise regularly.
3. How should I take Evopride 1/500mg if I miss a dose? Take the missed dose as soon as you remember, with food. If it’s nearly time for your next dose, skip the missed dose and return to your regular schedule. Do not double doses.
4. Is Evopride 1/500mg safe during pregnancy? The safety of Evopride 1/500mg during pregnancy is not established. Use only if clearly needed and prescribed by a healthcare provider.
5. What should I avoid while taking Evopride 1/500mg? Avoid consuming alcohol as it may increase the risk of lactic acidosis with Metformin and can interfere with blood sugar control.