Orinase-Met 2.0/500mg Tablet

Orinase-Met 2.0/500mg Tablet is a combination medication containing two active ingredients: Glimepiride and Metformin. Glimepiride belongs to the sulfonylurea class of antidiabetic agents, while Metformin is a biguanide antidiabetic medication. This combination is prescribed for the management of type 2 diabetes mellitus to help control blood sugar levels.

Composition:

Each Orinase-Met 2.0/500mg Tablet contains:

• Glimepiride 2.0mg: It stimulates the release of insulin from pancreatic beta cells, thereby reducing blood sugar levels.
• Metformin Hydrochloride 500mg: It improves insulin sensitivity, reduces hepatic glucose production, and enhances glucose utilization in peripheral tissues.

Uses:

1. Control of Blood Sugar Levels: Orinase-Met 2.0/500mg Tablet is used to lower and control blood sugar levels in patients with type 2 diabetes mellitus.
2. Adjunct to Diet and Exercise: It is prescribed as an adjunct to diet and exercise to achieve glycemic control in patients who have not adequately responded to lifestyle modifications alone.
3. Prevention of Diabetes-Related Complications: By helping to maintain blood sugar levels within the target range, Orinase-Met 2.0/500mg Tablet may reduce the risk of long-term complications associated with diabetes.

Dosage and Administration:

Orinase-Met 2.0/500mg Tablet should be taken orally with meals, usually once or twice daily, as prescribed by your healthcare provider. The dosage regimen may vary depending on individual patient factors and response to treatment. Swallow the tablet whole with a glass of water, and do not crush, chew, or break it.

Side Effects:

Common side effects associated with Orinase-Met 2.0/500mg Tablet may include:

1. Nausea or vomiting
2. Diarrhea
3. Abdominal discomfort or pain
4. Headache
5. Dizziness
6. Hypoglycemia (low blood sugar)
7. Metallic taste in the mouth (with Metformin)

Inform your doctor if any side effects persist or become bothersome.

Precautions:

Before using Orinase-Met 2.0/500mg Tablet, consider the following precautions:

1. Monitor Blood Sugar Levels: Regular monitoring of blood glucose levels is essential to assess the effectiveness of treatment and adjust the dosage of Orinase-Met accordingly to minimize the risk of hypoglycemia or hyperglycemia.
2. Avoid Alcohol: Limit or avoid alcohol consumption while taking Orinase-Met, as it may potentiate the risk of hypoglycemia.
3. Use in Pregnancy and Lactation: Use Orinase-Met with caution during pregnancy and breastfeeding, as safety data in these populations are limited. Consult your doctor for personalized recommendations.
4. Risk of Hypoglycemia: Be aware of the signs and symptoms of hypoglycemia (such as sweating, tremors, palpitations, confusion) and take appropriate measures to treat low blood sugar episodes promptly.
5. Interactions with Other Medications: Inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, as they may interact with Orinase-Met and affect blood sugar control.

When Not to Use:

Orinase-Met 2.0/500mg Tablet should not be used in the following circumstances:

1. Hypersensitivity: Individuals with a known allergy to Glimepiride, Metformin, or any components of the tablet should avoid its use.
2. Type 1 Diabetes: Orinase-Met is not indicated for the treatment of type 1 diabetes mellitus (insulin-dependent diabetes).

FAQs:

1. How does Orinase-Met 2.0/500mg Tablet work to lower blood sugar levels? Glimepiride stimulates the release of insulin from pancreatic beta cells, while Metformin improves insulin sensitivity and reduces hepatic glucose production, leading to decreased blood sugar levels.
2. What should I do if I miss a dose of Orinase-Met 2.0/500mg Tablet? If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
3. Can Orinase-Met 2.0/500mg Tablet be used alone for the treatment of diabetes? Orinase-Met is usually used in combination with diet and exercise for the management of type 2 diabetes mellitus. Your doctor may adjust your treatment regimen based on your individual needs and response to therapy.
4. Can Orinase-Met 2.0/500mg Tablet cause weight gain? Weight gain is a potential side effect of some antidiabetic medications, including Orinase-Met. Monitor your weight regularly and discuss any significant changes with your doctor.
5. Can Orinase-Met 2.0/500mg Tablet be used in elderly patients? Orinase-Met can be used in elderly patients with type 2 diabetes mellitus; however, caution should be exercised due to the increased risk of hypoglycemia and other adverse effects. Dosage adjustments may be necessary based on individual patient factors and renal function.