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NEO-PYROLATE INJECTION
BROOKES PHARMACEUTICAL LABS (PAK) LTD

Neo-Pyrolate Injection

₨ 2,063

In stock
Pack size10s
FormInjection
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Delivery in 2 to 3 working daysTo cities across Pakistan, delivery from ₨ 300
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About this product

Overview

NEO-PYROLATE INJECTION is a medication composed of Glycopyrrolate & Neostigmine Methylsulphate. Glycopyrrolate is an anticholinergic agent, while Neostigmine Methylsulphate is a cholinesterase inhibitor. This combination is commonly used in medical settings to reverse the effects of neuromuscular blockade induced by non-depolarizing neuromuscular-blocking agents.

Uses

  1. Reversal of Neuromuscular Blockade: NEO-PYROLATE INJECTION is primarily utilized to reverse neuromuscular blockade induced by non-depolarizing neuromuscular-blocking agents during surgical procedures or mechanical ventilation in intensive care units (ICUs).

Mechanism of Action

  1. Glycopyrrolate: Glycopyrrolate acts as an anticholinergic agent by competitively inhibiting the action of acetylcholine at muscarinic receptors, thereby reducing the effects of excessive cholinergic stimulation.
  2. Neostigmine Methylsulphate: Neostigmine Methylsulphate works by inhibiting the enzyme acetylcholinesterase, which breaks down acetylcholine. This inhibition leads to an increase in acetylcholine levels at the neuromuscular junction, thereby enhancing neuromuscular transmission.

Dosage and Administration

The dosage of NEO-PYROLATE INJECTION varies depending on factors such as the patient’s weight, the degree of neuromuscular blockade, and the specific neuromuscular-blocking agent used. It is typically administered intravenously under the supervision of a healthcare professional.

Precautions

  1. Bradycardia: NEO-PYROLATE INJECTION may cause bradycardia due to its anticholinergic effects. Close monitoring of heart rate is essential during administration, especially in patients with preexisting cardiac conditions.
  2. Hypersensitivity: Patients with a known hypersensitivity to Glycopyrrolate, Neostigmine Methylsulphate, or other components of the formulation should not receive NEO-PYROLATE INJECTION.

Side Effects

Common side effects associated with NEO-PYROLATE INJECTION include tachycardia, dry mouth, urinary retention, blurred vision, and gastrointestinal disturbances. Serious adverse reactions such as severe bradycardia or allergic reactions are rare but possible.

NEO-PYROLATE INJECTION containing Glycopyrrolate and Neostigmine Methylsulphate is used for reversing neuromuscular blockade induced by non-depolarizing neuromuscular-blocking agents during surgical procedures or mechanical ventilation. It works by antagonizing the effects of acetylcholine and enhancing neuromuscular transmission.

This information is for general awareness only. It does not replace advice from your doctor or pharmacist. Always read the leaflet and follow the directions you were given.

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