Mirena Device
Mirena Device ₨ 16,181
Back to products
Nimotop Tablet 30mg
Nimotop Tablet 30mg ₨ 1,307
Nexavar Tablet 200mg
BAYER PHARMA (PVT.) LTD

Nexavar Tablet 200mg

₨ 205,920

In stock
FormulaSorafenib (200mg)
Pack size60X10'S
FormTablet
Compare
Add to wishlist
Delivery in 2 to 3 working daysTo cities across Pakistan, delivery from ₨ 300
Cash on deliveryOr pay by bank transfer or card at checkout
Genuine productsFrom a DRAP-licensed pharmacy
Damaged or wrong item?We take it back. Read the return policy
Have a prescription? Upload it and our pharmacist will check your order.Questions about this product? WhatsApp 0336 3300001

About this product

Overview

Nexavar Tablet 200mg contains the active ingredient sorafenib, which is a kinase inhibitor medication. It is available in tablet form and is used in the treatment of certain types of cancer, including liver cancer (hepatocellular carcinoma), kidney cancer (renal cell carcinoma), and thyroid cancer.

Active Ingredient

Sorafenib: Sorafenib works by inhibiting multiple kinases involved in tumor cell proliferation and angiogenesis (the formation of new blood vessels that supply tumors). By targeting these pathways, sorafenib helps to slow down or stop the growth and spread of cancer cells.

Mechanism of Action

Sorafenib exerts its anticancer effects through several mechanisms, including inhibition of:

  • Raf kinase: This prevents the activation of downstream signaling pathways involved in cell proliferation.
  • Vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs): This inhibits angiogenesis, thereby reducing the blood supply to tumors.
  • Receptor tyrosine kinases (RTKs): Sorafenib blocks the activity of various RTKs involved in tumor cell survival and proliferation.

Uses

Nexavar Tablet 200mg is indicated for:

  • Treatment of advanced liver cancer (hepatocellular carcinoma) that cannot be removed by surgery.
  • Treatment of advanced kidney cancer (renal cell carcinoma) after the failure of prior systemic therapy.
  • Treatment of progressive, locally advanced, or metastatic differentiated thyroid carcinoma that is refractory to radioactive iodine treatment.

Dosage and Administration

The dosage of Nexavar Tablet 200mg should be individualized based on the patient’s condition, body weight, and tolerance to treatment. It is typically administered orally, with or without food, usually twice daily. The recommended dose for most indications is 400mg (two tablets) taken twice daily.

Side Effects

Common side effects of Nexavar Tablet 200mg may include:

  • Fatigue
  • Diarrhea
  • Skin rash
  • Hand-foot skin reaction (palmar-plantar erythrodysesthesia)
  • Hypertension (high blood pressure)
  • Nausea
  • Loss of appetite

Precautions

  • Patients taking Nexavar Tablet 200mg should undergo regular monitoring of blood pressure, liver function, and thyroid function.
  • Sorafenib may cause fetal harm if used during pregnancy, so it should not be used in pregnant women unless clearly necessary.
  • Breastfeeding should be avoided during sorafenib treatment.
  • Sorafenib may interact with certain medications, so it’s important to inform the healthcare provider about all current medications.

Nexavar Tablet 200mg, containing sorafenib, is a kinase inhibitor used in the treatment of advanced liver cancer, kidney cancer, and thyroid cancer. Its multitargeted activity against cancer cell proliferation and angiogenesis makes it an important therapeutic option for patients with these malignancies.

This information is for general awareness only. It does not replace advice from your doctor or pharmacist. Always read the leaflet and follow the directions you were given.

Customer reviews

0 reviews
0
0
0
0
0

Reviews

Clear filters

There are no reviews yet.

Be the first to review “Nexavar Tablet 200mg”