Sacvin 100mg Tablet
Sacvin 100mg Tablet ₨ 1,660
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Sacvin 50mg Tablet
PHARMEVO (PVT) LIMITED.

Sacvin 50mg Tablet

₨ 1,300

In stock
Pack size30s
FormTablet
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Delivery in 2 to 3 working daysTo cities across Pakistan, delivery from ₨ 300
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About this product

Overview

Sacvin 50mg Tablet is a pharmaceutical-grade medication containing a combination of sacubitril and valsartan as active ingredients. It is primarily used for the treatment of heart failure with reduced ejection fraction (HFrEF) in adults. Each tablet is meticulously formulated to provide 50mg of sacubitril and 50mg of valsartan, offering a standardized dosage for effective management of heart failure symptoms and improvement of cardiovascular outcomes.

Active Ingredients

  1. Sacubitril: Sacubitril is a neprilysin inhibitor that works by inhibiting the enzyme neprilysin, which is responsible for the degradation of natriuretic peptides. By inhibiting neprilysin, sacubitril increases the levels of natriuretic peptides, which promote vasodilation, diuresis, and natriuresis, ultimately improving heart failure symptoms.
  2. Valsartan: Valsartan is an angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that causes vasoconstriction and aldosterone release. By blocking angiotensin II receptors, valsartan dilates blood vessels, reduces blood pressure, and decreases the workload on the heart, thereby improving heart failure outcomes.

Uses

Sacvin 50mg Tablet is indicated for the treatment of heart failure with reduced ejection fraction (HFrEF), including:

  • Reduction of cardiovascular death and hospitalization for heart failure.
  • Improvement of symptoms such as dyspnea (shortness of breath), fatigue, and exercise intolerance.
  • Slowing the progression of heart failure and improving overall cardiovascular function.

Dosage and Administration

  • The recommended dosage of Sacvin 50mg Tablet is one tablet taken orally twice daily.
  • The tablet can be taken with or without food.
  • Dosage adjustments may be made by a healthcare professional based on individual response to treatment, renal function, and tolerability.
  • It is essential to follow the prescribed dosage and regimen to achieve optimal therapeutic benefits.

Precautions

  • Before initiating Sacvin 50mg Tablet, inform your healthcare provider about any allergies, medical conditions, or medications you are currently taking.
  • Monitor renal function and electrolyte levels regularly, especially in patients with renal impairment or volume depletion.
  • Use caution in patients with a history of angioedema or hypersensitivity reactions to ACE inhibitors or ARBs, as sacubitril/valsartan may increase the risk of angioedema.
  • Avoid concomitant use of Sacvin with ACE inhibitors, as it may increase the risk of angioedema and renal impairment.

Side Effects

Common side effects of Sacvin 50mg Tablet may include:

  • Hypotension (low blood pressure)
  • Hyperkalemia (elevated potassium levels)
  • Renal impairment
  • Dizziness
  • Cough
  • Fatigue

Serious side effects such as angioedema, renal failure, and hyperkalemia may occur rarely but require immediate medical attention.

Storage

  • Store Sacvin 50mg Tablet at room temperature away from moisture and heat.
  • Keep the tablets out of reach of children and pets.
  • Do not use Sacvin tablets after the expiration date printed on the packaging.

Tags

Sacvin 50mg Tablet, Sacubitril, Valsartan, Heart Failure, Reduced Ejection Fraction, Neprilysin Inhibitor, Angiotensin II Receptor Blocker, Cardiovascular Health, Medication.

Substitutes for Sacvin 50mg Tablet

These medicines contain the same salt as Sacvin 50mg Tablet (Sacubitril + Valsartan 50mg), so they are common substitutes. Compare their prices, and change brands only after checking with your doctor or pharmacist.

MedicineManufacturerPackPrice
Sacuvia 50mg TabletHighnoon Laboratories14sRs 707

Other strengths of Sacubitril + Valsartan

MedicineManufacturerStrengthPrice
Sacvin 100mg TabletPharmevo100mgRs 1,659.90

Frequently asked questions

How does Sacvin 50mg Tablet compare to other heart failure medications?

Sacvin 50mg Tablet combines the mechanisms of action of a neprilysin inhibitor (sacubitril) and an angiotensin II receptor blocker (valsartan) to provide comprehensive treatment for heart failure with reduced ejection fraction (HFrEF). It has been shown to reduce cardiovascular death and hospitalization for heart failure compared to ACE inhibitors alone.

Can Sacvin 50mg Tablet be used in patients with renal impairment?

Sacvin 50mg Tablet can be used in patients with renal impairment; however, dosage adjustments may be necessary based on the degree of renal dysfunction. Regular monitoring of renal function and electrolyte levels is recommended to ensure safety and efficacy.

What should I do if I miss a dose of Sacvin 50mg Tablet?

If you miss a dose of Sacvin 50mg Tablet, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Are there any dietary restrictions while taking Sacvin 50mg Tablet?

While taking Sacvin 50mg Tablet, it is essential to maintain a balanced diet and avoid excessive intake of potassium-rich foods or supplements, as hyperkalemia (elevated potassium levels) may occur. Consult your healthcare provider or a registered dietitian for personalized dietary recommendations.

Can Sacvin 50mg Tablet be used in pregnant or breastfeeding women?

Sacvin 50mg Tablet is not recommended for use during pregnancy due to the potential risk of fetal harm. It is also not recommended for use while breastfeeding, as it is unknown whether sacubitril/valsartan is excreted in human breast milk. Pregnant or breastfeeding women should consult their healthcare provider for alternative treatment options.

Health guide

high-blood-pressure-pakistan.jpgHigh Blood Pressure in Pakistan: Symptoms, Causes, and How to Control ItHigh blood pressure, or hypertension, is often called the silent killer, and the nickname is well earned. Most...Read the guide →

This information is for general awareness only. It does not replace advice from your doctor or pharmacist. Always read the leaflet and follow the directions you were given.

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