About this product
Overview
UBETRIL 24MG/26MG TABLET (Sacubitril & Valsartan) is a medication used to treat heart failure. It contains a combination of sacubitril, an angiotensin receptor neprilysin inhibitor (ARNI), and valsartan, an angiotensin receptor blocker (ARB).
Description
- Sacubitril and valsartan work together to improve heart function and reduce symptoms of heart failure.
- Sacubitril blocks the action of neprilysin, an enzyme that breaks down beneficial natriuretic peptides. By blocking neprilysin, sacubitril increases the levels of these peptides, which helps the heart function better.
- Valsartan blocks the action of angiotensin II, a hormone that constricts blood vessels and increases blood pressure. By blocking angiotensin II, valsartan relaxes blood vessels and reduces blood pressure.
Uses
- To treat heart failure with reduced ejection fraction (HFrEF) in adults.
- To reduce the risk of hospitalization for heart failure and improve overall heart function.
Benefits
- Improves heart function and reduces symptoms of heart failure.
- Reduces the risk of hospitalization for heart failure.
- Can be used in combination with other heart failure treatments for improved outcomes.
Side Effects
- Common side effects include headache, cough, and diarrhea.
- Other side effects may include low blood pressure, angioedema (swelling of the face, lips, tongue, or throat), and kidney problems.
- Rarely, sacubitril-valsartan may cause serious allergic reactions, liver problems, or angina (chest pain).
When not to use
- If you have severe liver problems.
- If you are pregnant or breastfeeding.
- If you have a history of angioedema caused by treatment with an angiotensin converting enzyme (ACE) inhibitor.
- If you have a history of angioedema or hereditary angioedema.
It is important to inform your doctor of any medical conditions, allergies, or medications you are taking before starting treatment with UBETRIL 24MG/26MG TABLET (Sacubitril and Valsartan). Your doctor may need to adjust the dose or monitor you more closely for side effects.
Note: This information is not exhaustive and does not cover all possible precautions, side effects, or interactions. Please consult your doctor or healthcare provider for more information.
This information is for general awareness only. It does not replace advice from your doctor or pharmacist. Always read the leaflet and follow the directions you were given.
Substitutes for Ubetril 24mg/26mg Tablet
These medicines contain the same salt as Ubetril 24mg/26mg Tablet (Valsartan + Sacubitril 24mg/26mg), so they are common substitutes. Compare their prices, and change brands only after checking with your doctor or pharmacist.
| Medicine | Manufacturer | Pack | Price |
|---|---|---|---|
| Forhef 50mg 24mg/26mg Tablets | CCL Pharmaceuticals | 14 tablets | Rs 703 |
Other strengths of Valsartan + Sacubitril
| Medicine | Manufacturer | Strength | Price |
|---|---|---|---|
| Valbet 24+26mg Tablet | Searle Company Limitede Company | 26mg | Rs 680 |
| Valbit 97+103mg Tablet | Searle Company Limitede Company | 103mg | Rs 1,078 |
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