Gvia M 50/850mg Tablet

Gvia M 50/850mg Tablet is a combination medication that contains two active ingredients: sitagliptin & metformin. Sitagliptin is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, while metformin is a biguanide antidiabetic agent. This combination medication is prescribed for the management of type 2 diabetes mellitus to improve glycemic control through different mechanisms of action.

Ingredients:

1. Sitagliptin: Sitagliptin works by inhibiting the enzyme DPP-4, which increases the levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones help regulate blood glucose levels by stimulating insulin release and inhibiting glucagon secretion.
2. Metformin: Metformin primarily works by decreasing hepatic glucose production, enhancing insulin sensitivity in peripheral tissues, and reducing intestinal glucose absorption. It helps lower blood glucose levels by improving insulin action and reducing insulin resistance.

Uses:

Gvia M 50/850mg Tablet is prescribed for the following purposes:

• Management of type 2 diabetes mellitus: Gvia M 50/850mg Tablet helps improve glycemic control in adults with type 2 diabetes mellitus, either as initial therapy or in combination with other antidiabetic medications such as sulfonylureas or insulin.
• Reduction of fasting and postprandial blood glucose levels: The combination of sitagliptin and metformin helps lower fasting and postprandial blood glucose levels by targeting different pathways involved in glucose regulation.

Side Effects:

While Gvia M 50/850mg Tablet is generally well-tolerated, some individuals may experience side effects, including:

• Nausea or vomiting
• Diarrhea or abdominal discomfort
• Headache
• Hypoglycemia (low blood sugar) when used with other antidiabetic medications
• Nasopharyngitis (inflammation of the nose and throat)
• Upper respiratory tract infection

Rare but serious side effects may include lactic acidosis (a buildup of lactic acid in the blood), pancreatitis, or allergic reactions. If you experience any severe or persistent side effects, inform your healthcare provider promptly.

Precautions:

• Inform your healthcare provider about any pre-existing medical conditions, allergies, or medications you are currently taking before starting Gvia M 50/850mg Tablet.
• Take Gvia M 50/850mg Tablet as directed by your doctor. Follow the prescribed dosage, frequency, and duration of treatment to achieve optimal therapeutic outcomes and minimize the risk of adverse effects.
• Monitor your blood glucose levels regularly as directed by your healthcare provider and report any abnormal readings promptly.

When Not to Use:

Gvia M 50/850mg Tablet should not be used in individuals with:

• Known hypersensitivity or allergy to sitagliptin, metformin, or any components of the tablet
• Severe renal impairment (creatinine clearance <30 mL/min) or end-stage renal disease requiring dialysis
• Acute or chronic metabolic acidosis, diabetic ketoacidosis, or history of lactic acidosis
• Severe hepatic impairment or acute liver disease

FAQ:

1. How should Gvia M 50/850mg Tablet be taken?
   • Take Gvia M 50/850mg Tablet orally, with meals, as directed by your healthcare provider. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet unless instructed otherwise.
2. Can Gvia M 50/850mg Tablet be used alone or with other antidiabetic medications?
   • Gvia M 50/850mg Tablet can be used alone as monotherapy or in combination with other antidiabetic medications such as sulfonylureas or insulin, depending on the individual’s glycemic control and treatment goals.
3. Are there any special dietary considerations while taking Gvia M 50/850mg Tablet?
   • Maintain a balanced diet and lifestyle modifications, including regular exercise and weight management, to complement the effects of sitagliptin and metformin therapy on glycemic control. Follow a diet as recommended by your healthcare provider or dietitian.
4. Can Gvia M 50/850mg Tablet be used in children?
   • Gvia M 50/850mg Tablet may be used in children and adolescents for specific indications and under the guidance of a pediatrician or pediatric endocrinologist. Dosage adjustments may be necessary based on age and weight. Follow the dosage instructions provided by the healthcare provider.
5. How long can Gvia M 50/850mg Tablet be used continuously?
   • Gvia M 50/850mg Tablet is typically used for long-term treatment of type 2 diabetes mellitus. Follow your healthcare provider’s recommendations regarding the duration of treatment. Regular monitoring and evaluation of glycemic control are essential for optimal management of diabe